Results 11 to 20 of about 19,440 (215)

Medical devices in allergy practice

World Allergy Organization Journal, 2020
Medical devices provide people with some health benefits in terms of diagnosis, prevention, treatment, and monitoring of disease processes. Different medical specialties use varieties of medical devices more or less specific for them.
Todor A. Popov, Gianni Passalacqua, Sandra N. González-Díaz, Davor Plavec, Fulvio Braido, Jose-Luis García-Abujeta, Lawrence Dubuske, Philip Rouadi, Mário Morais-Almeida, Sergio Bonini, Lei Cheng, Ignacio J. Ansotegui   +11 more
doaj   +1 more source

Review of investigational medical devices' clinical trials and regulations in Africa as a benchmark for new innovations

Frontiers in Medical Technology, 2022
Medical technologies present a huge potential in improving global health playing a key role toward achieving Sustainable Development Goal 3 by 2030.
Brian Matovu, Mercy Takuwa, Charles Norman Mpaata, Fiona Denison, Noah Kiwanuka, Steff Lewis, John Norrie, Sam Ononge, Owen Muhimbise, Sharon Tuck, Maureen Dimitri Etuket, Robert T. Ssekitoleko   +11 more
doaj   +1 more source

Use of National Database of Health Insurance Claims and Specific Health Checkups for examining practical utilization and safety signal of a drug to support regulatory assessment on postmarketing drug safety in Japan

Frontiers in Medicine, 2023
The Pharmaceuticals and Medical Devices Agency (PMDA) has conducted many pharmacoepidemiological studies for postmarketing drug safety assessments based on real-world data from medical information databases.
Haruka Shida, Kazuhiro Kajiyama, Sono Sawada, Chieko Ishiguro, Mikiko Kubo, Ryota Kimura, Mai Hirano, Noriyuki Komiyama, Toyotaka Iguchi, Yukio Oniyama, Yoshiaki Uyama   +10 more
doaj   +1 more source

Effects of curcumin and nicorandil on nilotinib-induced QT interval prolongation in rats: A telemetry-based study

Pakistan Journal of Pharmaceutical Sciences
Background: Long QT syndrome (LQTS) is characterized by QT prolongation, ventricular arrhythmias and sudden death. Nilotinib (Nilo), a tyrosine kinase inhibitor used in chronic myeloid leukemia, prolongs QTc mainly through hERG (IKr) channel inhibition ...
Nusin Harmanci, Zuhal Kaltus, Ezgi Eroglu, Cigdem Cengelli Unel, Semra Yigitaslan, Basar Sirmagul Turkish Medicines, Medical Devices Agency, Ankara, Turkiye   +8 more
doaj   +1 more source

The assessment of xenogeneic bone immunotoxicity and risk management study

BioMedical Engineering OnLine, 2019
Background Xenogeneic bone has been widely used in a variety of clinical bone-related disease to promote bone healing and restore bone defects. However, the adverse effects of immune system limit its application in the clinic.
Xiaoxia Sun, Chenghu Liu, Yanping Shi, Chunling Li, Likui Sun, Li Hou, Xin Wang   +6 more
doaj   +1 more source

The regulation of medical devices and the role of the Medical Devices Agency [PDF]

British Journal of Clinical Pharmacology, 2001
This article reviews the regulation of medical devices in the UK and Europe and compares the regulatory regime with that for pharmaceuticals. The regulation of devices follows the ‘New Approach’ policy of the EC Commission and involves more self‐regulation and conformity assessment.
openaire   +2 more sources

Causation as a condition for liability of medical employees [PDF]

Zbornik Radova Pravnog Fakulteta u Nišu, 2019
In order to hold a health care worker or a health care institution liable for damage caused to the patient, it is necessary to determine the causation as one of the permanent conditions for establishing liability.
Manić Samir
doaj  

Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs

Cancer Cell International, 2018
Background Intrinsic chemoresistance of glioblastoma (GBM) is frequently owed to activation of the PI3K and MEK/ERK pathways. These signaling cascades are tightly interconnected however the quantitative contribution of both to intrinsic resistance is ...
Bodo Haas, Veronika Klinger, Christina Keksel, Verena Bonigut, Daniela Kiefer, Julia Caspers, Julia Walther, Maria Wos-Maganga, Sandra Weickhardt, Gabriele Röhn, Marco Timmer, Roland Frötschl, Niels Eckstein   +12 more
doaj   +1 more source

Cardiovascular risk of urate‐lowering drugs: A study using the National Database of Health Insurance Claims and Specific Health Checkups of Japan

Clinical and Translational Science, 2023
In the present study, we aimed to investigate the association between urate‐lowering drugs and cardiovascular events, primarily focusing on the risk of febuxostat and topiroxostat when compared with allopurinol in Japan.
Sono Sawada, Kazuhiro Kajiyama, Haruka Shida, Ryota Kimura, Yuki Nakazato, Toyotaka Iguchi, Yukio Oniyama, Chieko Ishiguro, Yoshiaki Uyama   +8 more
doaj   +1 more source

Hallucinations in medical devices

Artificial Intelligence in the Life Sciences
Computer methods in medical devices are frequently imperfect and are known to produce errors in clinical or diagnostic tasks. However, when deep learning and data-based approaches yield output that exhibit errors, the devices are frequently said to ...
Jason Granstedt, Prabhat Kc, Rucha Deshpande, Victor Garcia, Aldo Badano   +4 more
doaj   +1 more source