Results 241 to 250 of about 9,698,373 (354)

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

Use and Public Reporting of Predetermined Change Control Plans for AI-Enabled Medical Devices.

JAMA Health Forum
Dabek PA, Bourgeois FT, Stern AD, Zhu Y, Everhart AO.   +4 more
europepmc   +1 more source

Innovative Clinical Trial Approach for Evaluating Digital Medical Devices Under European Fast-Track Regulatory Frameworks. [PDF]

Stat Med
Ursino M, Boulet S, Collignon C, Francis-Oliviero F, Lhomme E, Porcher R, Saillour F, Varoquaux G, Vercamer V, Thiébaut R, Zohar S.   +10 more
europepmc   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

Orphan medical devices: addressing the regulatory and access gaps in the EU and US. [PDF]

Front Public Health
Akodad S, Haon B, Rochaix L, Stevens H.
europepmc   +1 more source

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

Cybersecurity breaches in medical devices: analyzing FDA safety communications in response to patient security concerns. [PDF]

Front Digit Health
Menon V.
europepmc   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Describing Inconsistencies in Pediatric Labeling of Medical Devices.

JAMA Netw Open
Zapotoczny G, Snitman A, Shah P, Bent M, Glicksberg BS, Bourgeois F, Bar-Cohen Y, Espinoza J.   +7 more
europepmc   +1 more source

Artificial Intelligence Applications in Medical Devices for Personalized Health Care Solutions: Systematic Review. [PDF]

J Med Internet Res
Ponnambalath Mohanadas H, Manikandan A, Ismail AF, Tucker N, Jaganathan SK.   +4 more
europepmc   +1 more source