Results 61 to 70 of about 19,440 (215)

Counterfeit drugs and medical devices in developing countries

Research and Reports in Tropical Medicine, 2014
Beverley D GlassSchool of Pharmacy and Molecular Sciences, James Cook University, Townsville, QLD, AustraliaAbstract: The World Health Organization has reported that counterfeit medicines potentially make up more than 50% of the global drug market, with ...
Glass BD
doaj  

Prescription trend and lactic acidosis in patients prescribed metformin before and after the revision of package insert for allowing metformin administration to patients with moderately decreased kidney function based on real-world data from MID-NET® in Japan

Frontiers in Medicine
IntroductionThis study was conducted to understand the impact of package insert (PI) revision in Japan on 18 June 2019 to allow metformin use for patients with moderately decreased kidney function (30 ≤ estimated glomerular filtration rate (eGFR) < 60 
Takashi Waki, Yusuke Okada, Yuki Kinoshita, Kazuhiro Kajiyama, Chieko Ishiguro, Yuki Nakazato, Ryota Kimura, Harumi Maniwa, Naoya Horiuchi, Toyotaka Iguchi, Yoshiaki Uyama   +10 more
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Risk of neutropenia in psoriasis patients prescribed anti-IL-23 antibody in comparison with anti-IL-17 antibody or adalimumab based on real-world data from the MID-NET® in Japan

Journal of Dermatological Treatment
Background To evaluate the risk of neutropenia during treatment with anti-IL-23 antibodies in patients with psoriasis.Method We conducted an observational study with cohort design using MID-NET® in Japan.
Yusuke Okada, Kazuhiro Kajiyama, Chieko Ishiguro, Takahiro Nonaka, Tomomi Komaki, Wataru Kuga, Noriyuki Komiyama, Toyotaka Iguchi, Naoya Horiuchi, Yoshiaki Uyama   +9 more
doaj   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Explainable Artificial Intelligence in the Field of Drug Research

Drug Design, Development and Therapy
Qingyao Ding,1 Rufan Yao,1 Yue Bai,1 Limu Da,1 Yujiang Wang,2 Rongwu Xiang,1,3,4 Xiwei Jiang,1 Fei Zhai1 1Faculty of Medical Devices, Shenyang Pharmaceutical University, Shenyang, Liaoning Province, People’s Republic of China; 2Department of Internal ...
Ding Q, Yao R, Bai Y, Da L, Wang Y, Xiang R, Jiang X, Zhai F   +7 more
doaj  

A compound analysis of medical device clinical trials registered in Africa on clinicaltrials.gov

Trials
Background Africa, specifically the Sub-Saharan region, has had numerous medical technology clinical trials to address the various healthcare challenges around infectious diseases, non-communicable diseases, and nutritional disorders it is facing ...
Brian Matovu, Mercy Takuwa, Charles Norman Mpaata, Noah Kiwanuka, Julius Mugaga, Racheal Patricia Nalwoga, Success Kamuhanda, Paula Kworekwa, Benedict Mulindwa, George William Jjuuko, Maria Klara Wolters, Marc P. Y. Desmulliez, Robert T. Ssekitoleko   +12 more
doaj   +1 more source

Nanocoatings for Medical Devices

, 2016
Recent developments integrating nanotechnology with electronics and computing are producing a large number of medical devices for health care. In this chapter, we focus on the advances made in the use of coatings to enhance functionality of dental implants, stents, hip prosthesis, and miscellaneous devices.
Waqar Ahmed, M. AlHannan, S. Yusuf, M. J. Jackson   +3 more
openaire   +2 more sources