Results 91 to 100 of about 11,426,298 (383)

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

An Integrated Intuitionistic Fuzzy Similarity Measures for Medical Problems [PDF]

International Journal of Computational Intelligence Systems, 2014
The purpose of this paper is to develop an integrated similarity measures model based on intuitionistic fuzzy sets. This integrated model has improved two similarity measures methods: (1) Ye (, 53, 91-97 (2011)) presented a novel cosine similarity ...
Kuo-Chen Hung, Pei-Kuang Wang
doaj   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Bases y particularidades del método clínico en la atención primaria de salud Basis and peculiarities of clinical method of primary health care

Revista Cubana de Medicina General Integral, 2011
El diagnóstico médico es la base de una atención de calidad a nuestros pacientes. Se realizó una revisión de la literatura nacional y de algunos trabajos extranjeros sobre el método clínico, su importancia, bases, procedimientos y características ...
José Díaz Novás, Bárbara Rosa Gallego Machado, Adela Calles Calviño   +2 more
doaj  

Unimodal-Uniform Constrained Wasserstein Training for Medical Diagnosis [PDF]

2019 IEEE/CVF International Conference on Computer Vision Workshop (ICCVW), 2019
The labels in medical diagnosis task are usually discrete and successively distributed. For example, the Diabetic Retinopathy Diagnosis (DR) involves five health risk levels: no DR (0), mild DR (1), moderate DR (2), severe DR (3) and proliferative DR (4).
Xiaofeng Liu, Xu Han, Yukai Qiao, Yi Ge, Jun Lu   +4 more
semanticscholar   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Medical diagnosis system and method with multispectral imaging [PDF]

, 1979
A skin diagnosis system includes a scanning and optical arrangement whereby light reflected from each incremental area (pixel) of the skin is directed simultaneously to three separate light filters, e.g., IR, red, and green.
Anselmo, V. J., Reilly, T. H.
core   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

A Novel Interval Three-Way Concept Lattice Model with Its Application in Medical Diagnosis

Mathematics, 2019
Medical diagnosis has been recognized as one of the key processes in clinical medicine, which determines diseases from some given symptoms. Nonetheless, previous works about medical diagnosis have some drawbacks because medical data are usually fuzzy ...
Junhua Hu, Dan Chen, Pei Liang
doaj   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source