Results 111 to 120 of about 10,069,788 (309)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Challenges and Applications of Bio-Sniffers for Monitoring Volatile Organic Compounds in Medical Diagnostics

open access: yesChemosensors
Bio-sniffers represent a novel detection technology that demonstrates significant potential in medical diagnostics. Specifically, they assess disease conditions and metabolic status through the detection of volatile organic compounds (VOCs) in exhaled ...
Yang Wang   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Sensitivity of Bayesian Networks to Noise in Their Parameters

open access: yesEntropy
There is a widely spread belief in the Bayesian network (BN) community that the overall accuracy of results of BN inference is not too sensitive to the precision of their parameters.
Agnieszka Onisko, Marek J. Druzdzel
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Sensitivity of Bayesian Networks to Errors in Their Structure

open access: yesEntropy
There is a widespread belief in the Bayesian network (BN) community that while the overall accuracy of the results of BN inference is not sensitive to the precision of parameters, it is sensitive to the structure.
Agnieszka Onisko, Marek J. Druzdzel
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Medical Center campus, 1953

open access: yes, 1953
This glass lantern slide features a map of the Medical Colleg of South Carolina Medical Center campus in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

A Novel Picture Fuzzy Similarity Measure: Theory and Practical Applications

open access: yesIEEE Access
Similarity metrics serve as valuable tools for evaluating the resemblance between two datasets. While intuitionistic fuzzy sets have been widely used, picture fuzzy sets present enhanced capabilities in capturing ambiguity and uncertainty within real ...
Abdul Haseeb Ganie   +3 more
doaj   +1 more source

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