Results 121 to 130 of about 10,069,788 (309)
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
This glass lantern slide features an aerial view of the Medical Center building of the Medical College of the State of South Carolina in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Skin, a vital organ acting as a protective barrier to the external environment, plays a pivotal role in overall human health. Early detection of skin diseases is essential, as untreated conditions can escalate to serious issues such as skin cancer.
Farhatullah +5 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
This glass lantern slide features a black and white photograph of the Medical College of South Carolina in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core
Pattern recognition in medical images using neural networks
The proposal of this research line is the search for alternatives to the resolution of complex problems where human knowledge should be apprehended in a general fashion.
Laura Cristina Lanzarini +1 more
doaj
The existing diagnostic methods for Alzheimer’s disease (AD) require considerable time and expense from patients, and approaches employing machine learning have also failed to address these issues.
do Young Kim +3 more
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Image compression for medical diagnosis using neural networks
Images compression is a widely studied topic. Conventional situations offer variable compression ratios depending on the image in question and, in general, do not yield good results for images that are rich in tones. This work is an application of images
Laura Cristina Lanzarini +3 more
doaj

