Pattern recognition in medical images using neural networks
The proposal of this research line is the search for alternatives to the resolution of complex problems where human knowledge should be apprehended in a general fashion.
Laura Cristina Lanzarini+1 more
doaj
DIAGNOSIS AND OPERATIVE TREATMENT OF GUNSHOT WOUNDS OF THE STOMACH AND INTESTINES.Read by Invitation in the Surgical Section of the Tenth International Medical Congress, August 8, 1890. [PDF]
N. SENN
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Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Image compression for medical diagnosis using neural networks
Images compression is a widely studied topic. Conventional situations offer variable compression ratios depending on the image in question and, in general, do not yield good results for images that are rich in tones. This work is an application of images
Laura Cristina Lanzarini+3 more
doaj
The Early Diagnosis of Pulmonary TuberculosisPost-Graduate Lecture delivered under the auspices of the Fellowship of Medicine in the hall of the Medical Society of London on March 2, 1931. [PDF]
A. J. Whiting
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TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Manual of Emergencies, Medical, Surgical and Obstetric: Their Pathology, Diagnosis and Treatment [PDF]
A. D. Campbell
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The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Diagnosis in daily practice. By Benjamin V. White, M.D., Assistant Clinical Professor of Medicine, Yale University School of Medicine, and Charles F. Geschickter, M.D., Professor of Pathology, Georgetown University Medical School. 9¾ × 7 in. Pp. 693 + xvi with 360 illustrations. 1948. Philadelphia and London: J. B. Lippincott Co. £4 10s. net [PDF]
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source