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Why Medical Professionalism Education? [PDF]
, 2012 The idea that medicine itself imposes certain obligations upon the physician probably originated in Greece. It is Socrates in the fifth century BC who first discussed medical professionalism.
연세대학교 의과대학
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Competency-Based Medical Education: Possibilities and Limitations [PDF]
, 2011 Competency and competency-based education are topics of great interest to educators and administrators at most stages of undergraduate and postgraduate medical training.
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
How Should Medical Education Be Planned for Medical Students’ Future? [PDF]
, 2014 This study focused on investigating the future medicine and health care industry paradigm shift and suggesting the right direction for the medical education system in order for students to be better prepared in the near future.
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Educação médica continuada online: potencial e desafios no cenário brasileiro
Revista Brasileira de Educação MédicaCom a intensa produção e veiculação de informações científicas, tornou-se difícil para o profissional médico manter-se atualizado com os recursos habituais. A necessidade de conhecer e de participar de processos de formação continuada se impõe.
Maria Teresa Meirelles Leite +3 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source