Results 61 to 70 of about 5,822,336 (301)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Selected chapters on medical emergencies

Onkologija
no English ...
Iztok Potočnik, Helena Lenasi, Martin Erak   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Medical Emergencies in Dental Practice: 2. Management of Specific Medical Emergencies

, 2009
In the second of two papers on the diagnosis and management of medical emergencies, the measures needed to manage specific medical emergencies are discussed. Each emergency requires a correct diagnosis for effective and safe management.
Mark Greenwood
core   +1 more source

Oncologic emergencies: a review [PDF]

, 2018
Cancer and its treatment include many medical emergencies. Hence taking care of these emergencies presents a challenge not only to the clinicians but also to the medical oncologists.
Minoti Baruah, Baruah, Minoti
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Medical emergencies in dental practice

, 2014
Introduction: Dentistry is a clinical activity potentially at risk of medical emergencies and dental practitioners need to be prepared to handle them effectively.
Pascal Augustin, Florian Laurent, Scott T Youngquist, Nicolas Segal   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Predictors of flight diversions and deaths for in-flight medical emergencies in commercial aviation.

, 2010
In-flight medical emergencies are clinically challenging and may result in aircraft diversions, which are costly and inconvenient, or in-flight deaths.
Rainer, Timothy H., Ong, Rose M., Hung, Kevin K. C., Chan, Emily, Graham, Colin A., Rainer, Timothy Hudson, Chan, Emily Y. Y., Hung, Kevin K.C., Cocks, Robert A., Chan, Emily Y.Y., Cocks, RA, Ong, RM, Hung, KK, Rainer, TH, Graham, CA, Kevin K. C. Hung   +15 more
core   +1 more source