Results 81 to 90 of about 5,822,336 (301)

Morbidity and mortality profile of patients seen in medical emergency unit of a Teaching Hospital in Nigeria: A 4-year audit

open access: yesSahel Medical Journal, 2018
Background: Ahmadu Bello University Teaching Hospital (ABUTH) Zaria is strategically located to serve as referral center for most stable and emergency cases in the northwestern part of Nigeria. Patients also come on self-referral.
Bello Yusuf Jamoh   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Main emergencies in maxillofacial surgery and their relationships with other medical specialties [PDF]

open access: yes
Background: Emergencies in maxillofacial surgery are numerous, and many require urgent medical intervention. Their diagnosis necessitates collaboration between the maxillofacial surgeon and other medical specialties, while effective treatment and ...
Dobromirov, Dobromir; Медицински университет Варна „Проф. д-р Параскев Стоянов“
core   +1 more source

Handling medical emergencies [PDF]

open access: yes, 2015
Medical emergencies can occur at any time in the dental surgery. Routine dental operations and procedures that generally cause no harm or distress to fit and normal patients may give rise to symptoms, alarming and of sudden onset, in patients ...
Naidoo, Sudeshni
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Medical emergencies in pregnancy

open access: yes, 2016
This chapter outlines medical emergencies in pregnancy. It discusses the guidelines for resuscitation in pregnancy, abdominal pain, headache and generally feeling unwell, convulsions, chest pain and discomfort, breathlessness and difficulties in ...
Sambit Mukhopadhyay   +6 more
core   +1 more source

Effectiveness of First Aid Education on High School Students in Thrissur District, Kerala

open access: yesNational Board of Examinations Journal of Medical Sciences
Background: First aid refers to prompt assistance or care given to any persons with either a minor or serious illness or injury to preserve life, prevent the condition from worsening, or promote recovery.
Aiswarya K Venugopal   +7 more
doaj   +1 more source

Competence of handling medical emergencies among dental graduates and post-graduate students – A cross-sectional questionnaire study

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2019
Introduction: Dentists are encountering a growing number of geriatric and medically compromised patients and at the same time are performing more invasive and possibly painful dental treatments.
Aveek Mukherji   +5 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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