Results 91 to 100 of about 5,822,336 (301)

Manual of eye emergencies : diagnosis and management /

, 2004
This revised 2nd edition is a completely new and unique approach to the subject, redesigned to be the essential clinical reference for anyone who treats emergency eye conditions in the primary care setting or emergency room. Well-presented information in
Webb, Lennox A.Eye emergencies., Webb, Lennox A.   +1 more
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

The relationship between job burnout and quality of work life in pre-hospital emergency staff: Descriptive-correlation study [PDF]

Journal of Multidisciplinary Care
Background and aims: Pre-hospital emergency staff are often faced with highly stressful situations, leading most often to occupational burnout. One of the crucial factors affecting job burnout is the quality of work life.
Reza Nabi-Amjad, Shahram Kaviyani, Hamidreza Sadeghi-Gandomani   +2 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

ANALYSIS OF LEGAL ASPECTS OF STORAGE OF MEDICAL PRODUCTS APPOINTED FOR MEDICAL AND SANITARY CONSEQUENCES OF EMERGENCIES MITIGATION [PDF]

, 2015
The article analyzes principal legal aspects of medical products storage, appointed for medical and sanitary consequences of emergencies mitigation. We have revealed that nowadays there is a whole range of legal gaps and uncertainties in the regulation ...
A. Kh. Gaisarov, G. Ya. Ibragimova, R. V. Nasyrov   +2 more
core   +1 more source

The effect of Mentorship Program on Self-Esteem, Anxiety and Learning Clinical Skills of Emergency Medical Students: A Randomized Controlled Trial

مراقبت پرستاری و مامایی ابن سینا, 2021
Background and Objective: Clinical education (mentorship program) is one of the most important aspects of education in the medical sciences. Therefore, this study was conducted to investigate the effect of mentorship program on self-esteem, anxiety and ...
Hamideh Mashalchi, Ferdos Pelarak, Somayeh Mahdavi Kian, Tayebeh Mahvar, Amin Abdolvand, Morteza Habibi Moghadam   +5 more
doaj  

Knowledge levels and training needs of dental students and resident dentists in the management of clinical emergencies [PDF]

Balkan Journal of Dental Medicine
Background/Aim: The aim of this study is to assess undergraduate and postgraduate dental students' knowledge, experience and attitudes to managing medical emergencies that may occur in dental practice. It will also assess the impact of first aid training
Cilli Beste, Kaplanoğlu Melike Beyza, Özden Mustafa Enes, Özden İdil, Sazak Öveçoğlu Hesna   +4 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source