Results 101 to 110 of about 5,822,336 (301)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Neurological emergencies in the perspective of the national core education program of medical education

, 2021
Neurological emergencies are serious problems that can cause death. In medical faculties studentsshould be well trained to deal with neurological emergencies. For this purpose neurological emergencieswere included in National Core Education Program (NCEP)
Çınar Tanrıverdi, Esra, Nas, Mehmet Akif   +1 more
core  

Emergencies, Disasters, and Health: The Need to Reconsider Health System Education and Preparedness [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Given the increasing occurrence and severity of disasters in recent decades, including earthquakes, floods, and pandemics, the health system’s responsibility for providing rapid, effective, and humane responses to crises has become more ...
Ameneh Marzban, Soheil Golzar Hamid
doaj  

Evaluate Management Performance and the Degree of Readiness Hospital Emergency in Critical Situations

Health in Emergencies & Disasters Quarterly, 2021
Background: Hospitals, especially their emergency departments, are among the first health systems affected by accidents and disasters. Because of its nature and obligation to provide the highest quality services, this department should have protocols for
Asma Bahranifard, Kobra Rahzani, Ali Akbar Maleki Rad, Mokhtar Malekpour   +3 more
doaj  

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Acute medical emergencies and practical procedures

, 2016
Chapter 1 covers the basic science and clinical topics relating to acute medical emergencies and practical procedures which trainees are required to learn as part of their basic training and demonstrate in the MRCP.

core   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Preparedness of Government Owned Dental Clinics for the Management of Medical Emergencies: A Survey of Government Dental Clinics in Lagos.

, 2015
Background: An emergency is a medical condition demanding immediate treatments.Objective: The aim of the study was to determine the knowledge and ability of dental surgeons in the management of medical emergencies and the availability of emergency drugs ...
Omokhuale, E, Babatunde, LB, Gbotolorun, OM, Osisanya, O   +3 more
core   +1 more source

Medical Emergencies in Commercial Air Transportation

, 2006
The paper presents medical emergencies during the flighttime. The focus is on the most common types and causes ofthese emergencies. World indicators show an increase in thepassenger number and accordingly, an increased number ofemergency conditions and ...
Stančić, Marin, Missoni, Eduard, Vuković Dijčinovski, Nataša   +2 more
core   +2 more sources