Results 51 to 60 of about 926,076 (267)

An Emerging Medical Giant

JACC: Cardiovascular Interventions, 2013
![Figure][1] My first trip to southern India was in the early 1990s at the beginning of the stent era. The conference featured speakers from around the world talking about the advantages of the stents that were available and several that were in development.
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Medical Emergencies and Operational Preparedness Among Dentists: A Scoping Review

Dentistry Journal
Background: Medical emergencies occur at varying rates across the globe. Given the significant effort invested in identifying them and assessing dentists’ preparedness to deliver treatment in these life-threatening conditions, a global overview was ...
Radu-Alexandru Iacobescu, Teofil Blaga, Raluca Dragomir, Ștefania-Crina Mihai, Petruța Moroșan, Anca Hăisan   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Formulation of guidelines to resolve medical emergencies in dental practice: An overview

Saudi Journal of Oral Sciences, 2016
Dentists are prone to face unpredictable medical emergency crises in their patients during dental practice. These seldom but usually occurring events require diagnosis for safe and effective management.
Farouk M Sakr, Kais G Al-Obaidy, Lokesh J Shetty, Fathy A Behery, Mansour K Assery, Abdel Nasser I Adam, Mohamed J Patel   +6 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Characteristics and outcomes of medical emergencies in dentistry – an 8-year review of emergency calls at an Australian dental hospital

Journal of Oral Medicine and Oral Surgery
Aims: This study aimed to review Medical Emergency Team (MET) calls made at a public dental hospital to examine medical emergencies in dentistry and identify if any factors were associated with spontaneous recovery or urgent medical transfer.
Tran Vincent, Mian Mustafa, Rao Arya, Chye Leila, Delpachitra Seth, Garg Krati   +5 more
doaj   +1 more source

Medical emergencies encountered in dental clinics: A study from the Eastern Province of Saudi Arabia

Journal of Family and Community Medicine, 2015
Objectives: To report the prevalence of medical emergencies in dental clinics and self-perceived competence of dentists in the Eastern Province of Kingdom of Saudi Arabia (KSA).
Mostafa Alhamad, Talib Alnahwi, Hassan Alshayeb, Ali Alzayer, Omran Aldawood, Adeeb Almarzouq, Muhammad A Nazir   +6 more
doaj   +1 more source