Results 61 to 70 of about 2,008,711 (315)

Accessing emergency rest centres in the UK - lesson learnt [PDF]

, 2011
Emergency rest centres (ERC) are premises that are used for the temporary accommodation of evacuees during an emergency situation. They form an important part of emergency response, by providing a focal point for receiving people and providing food ...
Kipling, J, Newton, R, Ormerod, M
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Assessment of Knowledge and self-rated emergency preparedness amongst undergraduate dental students in Lagos State: A pilot study

Advances in Human Biology, 2019
Background: A medical emergency is an unwanted, unexpected reaction or complication, and few studies that assessed the knowledge and competency about emergencies in the dental clinics in Nigeria have been focussed on dentists and interns.
Oluwaseun Fasoyiro, Afolabi Oyapero, Olubunmi O Onigbinde, Modupeore E Sorunke, Aliru Idowu Akinleye   +4 more
doaj   +1 more source

School of Continuing Studies Launches New Degree Program for Emergency Medicine Professionals [PDF]

, 2015
Starting this fall, RWU to offer new program aimed to help expand career opportunities for students and professionals in the emergency medical services ...
Public Affairs, Roger Williams University
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Causes of Medical Coma in Adult Patients at the University College Hospital, Ibadan Nigeria

Nigerian Postgraduate Medical Journal, 2011
Aims and objectives : Diseases of medical origin leading to coma account for 3 -15% of emergency hospital admissions in developed countries. There is dearth of data on causes of medical coma in adults in Nigeria in particular and Africa in general.
O R Obiako, S Oparah, A Ogunniyi
doaj  

Training emergency services’ dispatchers to recognise stroke: an interrupted time-series analysis [PDF]

, 2013
Background: Stroke is a time-dependent medical emergency in which early presentation to specialist care reduces death and dependency. Up to 70% of all stroke patients obtain first medical contact from the Emergency Medical Services (EMS).
A Berglund, A Worster, AD Lopez, AK Wagner, AW Wojner-Alexandrov, BH Buck, Caroline L Watkins, CD Deakin, Chris J Sutton, Department of Health, EH Gilbert, European Stroke Organization (ESO) Executive Committee and the ESO Writing Committee, Gary A Ford, Michael J Leathley, P Ramanujam, R Kothari, R Kothari, SP Jones, SP Jones, SP Jones, Stephanie P Jones, The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group, Tom Quinn   +22 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source