Results 91 to 100 of about 1,781,086 (356)

Assessment of the Barriers to Medical Error Reporting the Viewpoint of Nurses in Selected Hospitals of Ahvaz [PDF]

مراقبت پرستاری و مامایی ابن سینا, 2023
Background and Objective: Error reporting leads to changes in hospital processes and improved health outcomes. In this regard, this study aimed to examine the barriers to the reporting of medical errors from the viewpoint of nurses in selected hospitals ...
Sajad Vahedi, Samaneh Moradi, Mahdi Amraei, Shahrzad Atarzade, Shirin Kianpour, Mohsen Zare Nasiri   +5 more
doaj  

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

A critical reassessment of the role of mitochondria in tumorigenesis [PDF]

, 2005
<p><b>Background:</b> Mitochondrial DNA (mtDNA) is being analyzed by an increasing number of laboratories in order to investigate its potential role as an active marker of tumorigenesis in various types of cancer.
Abnet, Achilli, Achilli, Ana Vega, Anderson, Andrews, Antonio Salas, Bandelt, Bandelt, Bandelt, Bandelt, Bandelt, Bandelt, Chen, Chen, Chinnery, Chinnery, Coble, Cooper, Doug Turnbull, Fliss, Forster, Gattermann, Hagelberg, Hans-Jürgen Bandelt, Herrnstadt, Herrnstadt, Hibi, Hibi, Hochhauser, Imaizumi, Ingman, Jerónimo, Khrapko, Kirches, Kivisild, Kong, Kong, Liu, Nishikawa, Palanichamy, Petros, Polyak, Reddy, Richards, Rocha, Salas, Salas, Tully, Vega, Vincent Macaulay, Wong, Wong, Yao, Yao, Yao, Yao, Yeh, Yong-Gang Yao, Ángel Carracedo   +59 more
core   +4 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Using information to deliver safer care: a mixed-methods study exploring general practitioners’ information needs in North West London primary care [PDF]

, 2014
The National Health Service in England has given increasing priority to improving inter-professional communication, enabling better management of patients with chronic conditions and reducing medical errors through effective use of information.
Aylin, P, Car, J, Majeed, A, Mastellos, N   +3 more
core   +3 more sources

Refractive Error Development in Children with Intermittent Exotropia [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Background and Objective: Intermittent exotropia is the most common type of outward deviation of the eye in childhood. The association between myopia refractive error and intermittent exotropia has been shown in very few studies. This study was conducted
F Senobari, M Etezad Razavi, M Najjaran, H Ostadimoghaddam, E Bakhtiari   +4 more
doaj  

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Disclosure of Medical error [PDF]

, 2011
With the advancement of medical sciences, lives are being prolonged and practice of medicine is considered an art and no longer as science. ‘To Err is Human Report’ has been released and gives data of medical errors in United States which opened people’s
Lalani, Sharifa Bashir, Shaikh, Kiran
core   +1 more source

Developing a similarity searching module for patient safety event reporting system using semantic similarity measures

BMC Medical Informatics and Decision Making, 2017
Background The most important knowledge in the field of patient safety is regarding the prevention and reduction of patient safety events (PSE) during treatment and care.
Hong Kang, Yang Gong
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source