Assessment of the effectiveness of medical simulators in the practical training of medical students: Preliminary results in MU-Varna [PDF]
, 2019 INTRODUCTION: Nowadays, simulators have become part of most medical universities’ educational strategy. In recent years, Medical University of Varna has been equipped with the most modern medical simulators, aiming to meet the practical training needs of
Chernogorova, Yanita; Medical University of Varna +2 more
core +7 more sources
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Medical errors: Mandatory reporting, voluntary reporting, or both? [PDF]
This work evaluates policy recommendations on medical error reporting systems presented in, To err is human, a report published by the Institute of Medicine.
Grepperud, Sverre
core
, 2005 This resource is a curriculum guide designed to teach medical students and family practice residents about medical errors and patient safety—a glaring deficit in medical education.
Laurie Sullivan, Joseph Halbach
core +1 more source
Applying hierarchical task analysis to medication administration errors [PDF]
, 2006 Medication use in hospitals is a complex process and is dependent on the successful interaction of health professionals functioning within different disciplines.
Stanton, Neville A. +5 more
core +1 more source
Agreement between methods of retinoscopy, conventional subjective refraction and fogging subjective refraction [PDF]
Reviews in Clinical MedicinePurpose: to compare the refractive error measurements achieved through three distinct techniques: retinoscopy, subjective method, and the subjective fogging method. Methods: Participants included 223 young adults aged 18 to 36 years (mean age: 25.63±5.31)
Atefeh Kebriaei +6 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Incomplete penetrance in inborn errors of immunity: A skeleton in the closet—The sequelIncomplete penetrance [PDF]
Journal of Human ImmunityIncomplete penetrance in genetic disorders can be influenced by genetic variant quality, genetic and epigenetic modification, environment, and mosaicism.
Dusan Bogunovic
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source