Results 61 to 70 of about 7,356,761 (300)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Medical Errors and Barriers to Reporting in Ten Hospitals in southern Iran

, 2014
Background [International research has shown that medical errors are a major threat to patient safety.] Aims [The present study aimed to determine the frequency and barriers to reporting medical errors in Shiraz public hospitals, Iran.
Fateme Sotode Zadeh; School of Public Health, Tehran University of Medical Sciences, Tehran, Iran, Mohammad Khammarnia; Department of Health Services Management, School of Management and Medical Information, Shiraz University of Medical Sciences, Shiraz, Iran, Ramin Ravangard; Department of Health Services Management, School of Management and Medical Information, Shiraz University of Medical Sciences, Shiraz, Iran, Eshagh Barfar; Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran   +3 more
core   +3 more sources

Physicians’ and nurses’ medical errors associated with communication failures

, 2017
Objective: To determine medical errors associated with communication failures among physicians and nurses. Methods: This cross-sectional, descriptive study was conducted at 20 state hospitals and 14 training and research hospitals affiliated with the ...
Savaser, Sevim, Topcu, Ibrahim, Sen, Hanife, Türkmen, Ayse Sonay, Sahiner, Nejla Canbulat   +4 more
core   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Assessment of Nurses’ Perceived Barriers and Behaviors to Reporting Medication Errors in Hospitals of Lorestan University of Medical Sciences, Iran [PDF]

Background: Medication errors are the most common medical errors and are one of the major challenges threatening the health system. This study aimed to determine nurses’ perceived barriers and behaviors to reporting medication errors in 2011. Methods:
حیدری, حشمت اله, کامران, عزیز, پیرزاده, آسیه   +2 more
core  

Manifesto for medical research [PDF]

, 2015
The MRCG want to ensure there is a dynamic medical research environment in Ireland. Ensuring priority investment for medical research will help to deliver patient care, public health service transformation and economic and enterprise development.
Medical Research Charities Group
core  

Disclosure of Medical Errors: Attitudes of Iranian Internists and Surgeons [PDF]

, 2013
Background: Despite the widespread prevalence of medical errors and increased concerns of healthcare managers and the public about the disclosure of medical errors in recent decades, existing evidence shows that physicians still ignore the importance of ...
Sheikhazadi, A, Mesri, M, Tagaddosinejad, F, Mostafazadeh, B, Farahani, M   +4 more
core   +1 more source

Functional studies in a neonate with a DOCK11 VUS guide clinical careFunctional studies of a DOCK11 VUS [PDF]

Journal of Human Immunity
O’Connell et al. demonstrate that negative functional studies can meaningfully guide care. In a neonate with a DOCK11 variant of uncertain significance, negative functional studies guide clinical care and highlight the broader value of publishing ...
Patrick O’Connell, Conor Gruber, Sofija Buta-Panov, Jaya Ganesh, NY-ROYAL Consortium, Dusan Bogunovic   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source