Results 91 to 100 of about 1,901,010 (298)
Medical errors: Mandatory reporting, voluntary reporting, or both? [PDF]
This work evaluates policy recommendations on medical error reporting systems presented in, To err is human, a report published by the Institute of Medicine.
Grepperud, Sverre
core
The Promise of Health Information Technology: Ensuring that Florida's Children Benefit [PDF]
, 2008 Substantial policy interest in supporting the adoption of Health Information Technology (HIT) by the public and private sectors over the last 5 -- 7 years, was spurred in particular by the release of multiple Institute of Medicine reports documenting the
Lisa Simpson, Wendy Struchen-Shellhorn
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Smartphone applications for early screening of retinoblastoma: a scoping review
BMC OphthalmologyIntroduction Retinoblastoma is the most common intraocular malignancy in childhood, typically presenting before five years of age. Early detection is essential in improving survival and visual outcomes.
Kartiekasari Syahidda Mohammad Zubairi +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Criminal Liability for Multiple Medical Errors
Arab Journal of Forensic Sciences & Forensic Medicine, 2016 Medical errors that result in the harm or death of patients are still a major problem in health sectors all over the world. Identifying the cause of a medical error can be a difficult task because a large number of medical procedures involve the ...
Mohammad Fathi Shahta Ebrahim +1 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Refractive Error Development in Children with Intermittent Exotropia [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i BābulBackground and Objective: Intermittent exotropia is the most common type of outward deviation of the eye in childhood. The association between myopia refractive error and intermittent exotropia has been shown in very few studies. This study was conducted
F Senobari +4 more
doaj
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source