Results 121 to 130 of about 1,911,499 (379)

WangLab at MEDIQA-CORR 2024: Optimized LLM-based Programs for Medical Error Detection and Correction [PDF]

open access: yesarXiv
Medical errors in clinical text pose significant risks to patient safety. The MEDIQA-CORR 2024 shared task focuses on detecting and correcting these errors across three subtasks: identifying the presence of an error, extracting the erroneous sentence, and generating a corrected sentence.
arxiv  

Reliable Multi-modal Medical Image-to-image Translation Independent of Pixel-wise Aligned Data [PDF]

open access: yes
The current mainstream multi-modal medical image-to-image translation methods face a contradiction. Supervised methods with outstanding performance rely on pixel-wise aligned training data to constrain the model optimization. However, obtaining pixel-wise aligned multi-modal medical image datasets is challenging.
arxiv   +1 more source

Medical Errors in Cyprus: The 2005 Eurobarometer Survey [PDF]

open access: yes, 2012
Background: Medical errors have been highlighted in recent years by different agencies, scientific bodies and research teams alike. We sought to explore the issue of medical errors in Cyprus using data from the Eurobarometer survey.Methods: Data from the
Andreas Pavlakis   +1 more
core  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

m1: Unleash the Potential of Test-Time Scaling for Medical Reasoning with Large Language Models [PDF]

open access: yesarXiv
Test-time scaling has emerged as a powerful technique for enhancing the reasoning capabilities of large language models. However, its effectiveness in medical reasoning remains uncertain, as the medical domain fundamentally differs from mathematical tasks in terms of knowledge representation and decision-making processes.
arxiv  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Resolving ethical dilemma: An application of a theoretical model [PDF]

open access: yes, 2014
Human error can occur in any profession. Medical errors most commonly occur in a health care system, which may delay patient’s recovery and produce harm to patients.
Amlani, Gulzar   +2 more
core   +1 more source

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