Results 141 to 150 of about 1,911,499 (379)

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Measurement errors in medical research

open access: yesPayesh, 2010
To address research questions, measuring variables are neccessary. However, every measurement is prone to different types of measurement errors. Therefore, understanding about the different types of measurement errors are a great of importance This paper
Masumeh Sadeghi   +2 more
doaj  

Physician Income Prediction Errors: Sources and Implications for Behavior [PDF]

open access: yes
Although income expectations play a central role in many economic decisions, little is known about the sources of income prediction errors and how agents respond to income shocks.
Nicholas S. Souleles, Sean Nicholson
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

SilVar-Med: A Speech-Driven Visual Language Model for Explainable Abnormality Detection in Medical Imaging [PDF]

open access: yesarXiv
Medical Visual Language Models have shown great potential in various healthcare applications, including medical image captioning and diagnostic assistance. However, most existing models rely on text-based instructions, limiting their usability in real-world clinical environments especially in scenarios such as surgery, text-based interaction is often ...
arxiv  

A Graph Framework for Multimodal Medical Information Processing [PDF]

open access: yesarXiv, 2016
Multimodal medical information processing is currently the epicenter of intense interdisciplinary research, as proper data fusion may lead to more accurate diagnoses. Moreover, multimodality may disambiguate cases of co-morbidity. This paper presents a framework for retrieving, analyzing, and storing medical information as a multilayer graph, an ...
arxiv  

Mitigation of Preventable Medical Errors via the use of Human Resources and Human Factors [PDF]

open access: yes, 2015
The purpose of this thesis is to discuss historical and current rates of preventable medical errors (PMEs), their causes, and methods used to reduce them.
Creel, Callender
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

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