Results 41 to 50 of about 1,773,840 (355)

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Immunization coverage and timeliness of vaccination in young patients with inborn errors of metabolism: a French multicentric study

open access: yesOrphanet Journal of Rare Diseases
Background Inborn errors of metabolism (IEMs) are rare disorders that are heterogeneous in severity and clinical presentation. Patients with IEMs should receive the vaccination schedule recommended for the whole population, and specific vaccinations ...
Anne-Sophie Renous   +11 more
doaj   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Identifying Harm Events in Clinical Care through Medical Narratives

open access: yes, 2017
Preventable medical errors are estimated to be among the leading causes of injury and death in the United States. To prevent such errors, healthcare systems have implemented patient safety and incident reporting systems.
Cohan, Arman   +3 more
core   +1 more source

Repeatability and Agreement of Anterion with Pentacam HR and Orbscan II in Corneal Parameters after Photorefractive Keratectomy

open access: yesDubai Medical Journal
Introduction: This study aimed to evaluate the repeatability and agreement of Anterion with Pentacam HR and Orbscan II in corneal parameters after photorefractive keratectomy (PRK).
Hadi Ostadi-Moghaddam   +6 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

A Neural Attention Model for Categorizing Patient Safety Events

open access: yes, 2017
Medical errors are leading causes of death in the US and as such, prevention of these errors is paramount to promoting health care. Patient Safety Event reports are narratives describing potential adverse events to the patients and are important in ...
JL Elman   +6 more
core   +1 more source

Reducing medical errors in primary care using a pragmatic complex intervention [PDF]

open access: yes, 2015
This study aimed to develop an intervention to reduce medical errors and to determine if the intervention can reduce medical errors in public funded primary care clinics. A controlled interventional trial was conducted in 12 conveniently selected primary
A. Hamid, Maimunah   +7 more
core   +1 more source

Inpatients’ medical prescription errors [PDF]

open access: yesEinstein (São Paulo), 2009
Objective: To identify and quantify the most frequent prescription errors in inpatients’ medical prescriptions. Methods: A survey of prescription errors was performed in the inpatients’ medical prescriptions, from July 2008 to May 2009 for eight hours a ...
Aline Melo Santos Silva
doaj  

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