Results 41 to 50 of about 1,825,467 (355)

Repeatability and Agreement of Anterion with Pentacam HR and Orbscan II in Corneal Parameters after Photorefractive Keratectomy

open access: yesDubai Medical Journal
Introduction: This study aimed to evaluate the repeatability and agreement of Anterion with Pentacam HR and Orbscan II in corneal parameters after photorefractive keratectomy (PRK).
Hadi Ostadi-Moghaddam   +6 more
doaj   +1 more source

Medication errors [PDF]

open access: yesNurse Prescribing, 2018
In its report of the Short Life Working Group on reducing medication-related harm, the Department of Health and Social Care (DHSC) (2018) provided a UK response to the World Health Organization's (WHO) (2017) Global Patient Safety Challenge, ‘Medication without Harm’. WHO (2017) recognised that there is significant harm caused to patients globally as a
openaire   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Safety and the flying doctor [PDF]

open access: yes, 2008
Interest, curiosity, or dismay—which feeling predominates when we learn from BBC Newsnight that our NHS employs doctors who commute from Poland to cover the out of hours duties that local GPs are unable to work because they are too tired at night?
Cappuccio, Francesco, Lockley, Steven B.
core   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Medical errors: An observational study

open access: yesJournal of Pediatric Critical Care, 2018
Introduction: Medical errors or negligence is leading cause of morbidity and mortality in many countries. Preventive and corrective measures can help in reduction of such events thus causing less damage and economic loss.
Kundan Mittal
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Disclosing Medical Errors to Patients

open access: yesMedEdPORTAL, 2010
This is a standardized patient case that has been used to assess the communication skills of radiology residents when disclosing a medical error to a patient. In the case, a 50-year-old woman brings her young adult son for a CT scan.
Win May, Beverly Wood
doaj   +1 more source

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