Results 51 to 60 of about 7,713,906 (370)

Teaching medical ethics symposium. Medical ethics in Manchester. [PDF]

Journal of Medical Ethics, 1987
Manchester's multi-disciplinary approach to medical ethics combines established methods and new initiatives. There is a longstanding Medical Group and also, plans are evolving for the inclusion of medical ethics teaching in the undergraduate curriculum, the start of an MA in Health Care Ethics in October 1987 and the establishment of the Centre for ...
Brazier, M., Dyson, A., Harris, J., Lobjoit, M.   +3 more
openaire   +4 more sources

Implementing advance care planning in nursing homes – study protocol of a cluster-randomized clinical trial

BMC Geriatrics, 2018
Background Close to half of all deaths in Norway occur in nursing homes, which signals a need for good communication on end-of-life care. Advance care planning (ACP) is one means to that end, but in Norwegian nursing homes, ACP is not common.
Trygve Johannes Lereim Sævareid, Lillian Lillemoen, Lisbeth Thoresen, Reidun Førde, Elisabeth Gjerberg, Reidar Pedersen   +5 more
doaj   +1 more source

An Overview of Artificial Intelligence Ethics

IEEE Transactions on Artificial Intelligence, 2023
Artificial intelligence (AI) has profoundly changed and will continue to change our lives. AI is being applied in more and more fields and scenarios such as autonomous driving, medical care, media, finance, industrial robots, and internet services.
Changwu Huang, Zeqi Zhang, Bifei Mao, X. Yao   +3 more
semanticscholar   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Guideline for ethics review of clinical trials

Holistic Integrative Oncology
This article is the first ethical review technical guideline in the field of oncology in China, compiled by the Medical Ethics Society of China Anti-Cancer Association and jointly completed by 104 national ethics review experts in accordance with a ...
Medical Ethics Society of China Anti-Cancer Association, Minghuang Hong, Zhao Yan   +2 more
doaj   +1 more source

Ethical approval in developing countries is not optional [PDF]

, 2012
When conducting health and medical research it is not only important to do the research ethically, but also to apply for prior ethical approval from the relevant authorities.
Simkhada, Padam, van Teijlingen, Edwin
core   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

How to introduce medical ethics at the bedside - Factors influencing the implementation of an ethical decision-making model

BMC Medical Ethics, 2017
BackgroundAs the implementation of new approaches and procedures of medical ethics is as complex and resource-consuming as in other fields, strategies and activities must be carefully planned to use the available means and funds responsibly.
Barbara Meyer-Zehnder, H. Albisser Schleger, S. Tanner, V. Schnurrer, D. Vogt, S. Reiter-Theil, H. Pargger   +6 more
semanticscholar   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source