Results 141 to 150 of about 2,147,772 (296)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Brining a Change in Medical Education

open access: yes, 2011
Every medical school aims to provide better education, and it sometimes requires changing the current education system. However, an attempt for a change may not always be successful. In many cases, it is so not because an intended change was not properly
연세대학교 의과대학
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

THE DECREASE OF AIRLINE OCCUPATIONAL ENVIRONMENTAL RISK FACTORS. LEGISLATIVE AND MEDICAL ASPECTS

open access: yesНаучный вестник МГТУ ГА, 2017
Russian Federation is entering a new system of Occupational standards as norm of competence that people are expected to achieve in their work, and the knowledge and skills they need to apply effectively.
V. E. Andrusov, Y. G. Khudyakov
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Sexism in a UK-wide medical examination. [PDF]

open access: yesClin Med (Lond), 2022
Fox SE, Paxton B.
europepmc   +1 more source

Improvement in Clinical Performance of Interns and Residents through Clinical Skills Assessment of the Korean Medical Licensing Examination [PDF]

open access: yes, 2012
Purpose To evaluate the clinical performance through the Korean Medical Licensing Examination clinical skills assessment (KMLE CSA) this survey was done.
박인철, 장후선, 박은철
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Performance of ChatGPT on the Peruvian National Licensing Medical Examination: Cross-Sectional Study. [PDF]

open access: yesJMIR Med Educ, 2023
Flores-Cohaila JA   +6 more
europepmc   +1 more source

New Challenges for Korean Medical Education: Enhancing Students’ Abilities to Deal with Uncertain Ill‐Defined Problems

open access: yes, 2014
Over the last century, medical education in North America has evolved by identifying educational challenges within its own socio-cultural context and by appropriately responding to these challenges.
연세대학교 의과대학
core  

Home - About - Disclaimer - Privacy