Results 151 to 160 of about 2,040,332 (267)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Association of Control Service Types with Aviation Medical Examination Results and Sick Leave in Air Traffic Controllers in Korea. [PDF]

Healthcare (Basel)
Choi JH, Jung HS, Choi EH.
europepmc   +1 more source

Males as victims of intimate partner violence - results from a clinical-forensic medical examination centre. [PDF]

Int J Legal Med, 2021
Wörmann X, Wilmes S, Seifert D, Anders S.   +3 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Evaluation of large language models under different training background in Chinese medical examination: a comparative study. [PDF]

Front Artif Intell
Zhang S, Chu Q, Li Y, Liu J, Wang J, Yan C, Liu W, Wang Y, Zhao C, Zhang X, Chen Y.   +10 more
europepmc   +1 more source

[Simulation in the elective subject forensic medicine in the third section of the medical examination]. [PDF]

Rechtsmedizin (Berl), 2023
Stoevesandt D, Woydt L, Steglich J, Lessig R, Rudzki M, Schlitt A, Weber M.   +6 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Comparison of the Performance of Artificial Intelligence Versus Medical Professionals in the Polish Final Medical Examination. [PDF]

Cureus
Jaworski A, Jasiński D, Jaworski W, Hop A, Janek A, Sławińska B, Konieczniak L, Rzepka M, Jung M, Sysło O, Jarząbek V, Błecha Z, Haraziński K, Jasińska N.   +13 more
europepmc   +1 more source

Quality management of the periodic medical examination at a university hospital, from the workers' perspective. [PDF]

Rev Bras Med Trab, 2022
Toniasso SCC, Brum MCB, Hirakata VN, Schlatter RP.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source