Results 31 to 40 of about 2,040,332 (267)

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Mechanism and role of H. pylori CagA-induced NLRP3 inflammasome in gastric cancer immune cell infiltration

Scientific Reports
The high incidence of gastric cancer in China is strongly associated with widespread Helicobacter pylori infection. While the bacterium’s role in gastric cancer initiation and progression is well-established, the precise molecular mechanisms remain ...
Chuandan Wan, Ping Wang, Yeqiong Xu, Yanping Zhu, Huanhuan Chen, Xuexian Cao, Yulan Gu   +6 more
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

On the Quality of Medical Examination: Diagnostic Significance of the Survey Method for Detecting the Probability of Cardio-Cerebral Symptoms

Рациональная фармакотерапия в кардиологии, 2020
Aim. To evaluate the effectiveness of the survey method for detecting the probability of cardio-cerebral symptoms and diseases as an indicator of the quality of its use in the framework of medical examination.Material and methods.
A. M. Kalinina, K. A. Antonov, B. E. Gornyi, I. I. Dubovoj, O. M. Drapkina   +4 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Good Preclinical Study, as an Obligatory Stage in Design and Clinical Use of New Medicinal Preparations

Антибиотики и Химиотерапия, 2020
Preclinical studies are investigations, performed in vitro and in vivo (on animals) prior to clinical trials in men. They play the main role in design of medicinal preparations.
A. N. Vasilyev
doaj  

Suicide in a shooting range: A review of two autopsy cases [PDF]

Srpski Arhiv za Celokupno Lekarstvo
Introduction. Shooting ranges are places designated for firearm shooting practice. Regulations outline the technical and structural requirements, that should ensure the safety of individuals inside the shooting range.
Marinković Nadica, Aleksić Ivan
doaj   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source

OPTIMIZATION OF MEDICAL EXAMINATION OF BLOOD DONORS AS AN ELEMENT OF LEAN HEALTHCARE IN NOVOSIBIRSK CLINICAL BLOOD CENTER

Сибирский научный медицинский журнал, 2019
Objective was to assess the possibility of optimizing the process of medical examination of blood donors and its components based on the principles of lean health care, to reduce the average working time of the sites involved in the procedure of medical ...
Yu. V. Moor, K. V. Khalzov, T. I. Pospelova   +2 more
doaj   +1 more source