Bayesian clinical trial designs : Another option for trauma trials? [PDF]
, 2017 The UK-REBOA Trial is funded by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme (project number 14/199/09). PP was supported by the MRC Network of Hubs for Trials Methodology Research (MR/L004933/1-R/N/P/B1).
Campbell, Marion K. +4 more
core +2 more sources
When can Muslims withdraw or withhold life support? A narrative review of Islamic juridical rulings
Global Bioethics, 2020 When it is ethically justifiable to stop medical treatment? For many Muslim patients, families, and clinicians this ethical question remains a challenging one as Islamic ethico-legal guidance on such matters remains scattered and difficult to interpret ...
Afshan Mohiuddin +3 more
doaj +1 more source
Attaining Good End-of-Life Care in Intensive Care Units in Taiwan—The Dilemma And the Strategy
International Journal of Gerontology, 2009 One of the major challenges for intensivists is resolving the conflicting interests in end-of-life care. We reviewed patients' characteristics in an intensive care unit to determine the major barriers of practicing good end-of-life care and the medical ...
Shih-Yi Lee +8 more
doaj +1 more source
Study protocol for THINK : a multinational open-label phase I study to assess the safety and clinical activity of multiple administrations of NKR-2 in patients with different metastatic tumour types [PDF]
, 2017 Introduction: NKR-2 are autologous T cells genetically modified to express a chimeric antigen receptor (CAR) comprising a fusion of the natural killer group 2D (NKG2D) receptor with the CD3 zeta signalling domain, which associates with the adaptor ...
Aftimos, Philippe +15 more
core +1 more source
Predictors of consciousness improvement in patients with hypoglycemic encephalopathy
Frontiers in Endocrinology, 2022 AimsHypoglycemic encephalopathy (HE) can cause long-lasting mental changes, disability, and even death. We aimed to investigate prognostic factors for HE and to determine when the treatment of HE becomes futile.MethodsWe retrospectively evaluated the ...
Yu Eun Lee +3 more
doaj +1 more source
Communication challenges in end-of-life decisions
Swiss Medical Weekly, 2020 With the progress in healthcare over recent decades and a growing life expectancy, discussions and decisions regarding end-of-life issues have become increasingly important. Especially in intensive care and emergency medicine there is a growing need of
Christoph Becker +3 more
doaj +1 more source
Ethical Issues in Family Practice: Medical Futility — The debate
South African Family Practice, 2004 No abstract available.
D. Knapp van Bogaert, G.A. Ogunbanjo
doaj +1 more source
A phase II multicentre, open-label, proof-of-concept study of tasquinimod in hepatocellular, ovarian, renal cell, and gastric cancers [PDF]
, 2017 Background: Tasquinimod is a small molecule with immunomodulatory, anti-angiogenic, and anti-metastatic properties that targets the tumor microenvironment.
Bjarnason, Georg A +14 more
core +1 more source
Characteristics and Outcomes of Potentially Inappropriate Admissions to the Intensive Care Unit [PDF]
Acute and Critical Care, 2019 Background Admission of patients perceived as potentially inappropriate for intensive care is a very sensitive and controversial issue. We aimed to evaluate the use of medical resources in the intensive care unit (ICU) and outcomes of patients according ...
Sooim Sin, Sang-Min Lee, Jinwoo Lee
doaj +1 more source
Withdrawing Medically Futile Treatment [PDF]
Journal of Oncology Practice, 2009 Physicians confront clinical and ethical dilemmas when their patients wish to continue treatments they have deemed futile; they must consider ethical obligations in deciding whether treatment should be withdrawn and in transferring patients from futile treatment to supportive care.
Dianna S, Howard, Timothy M, Pawlik
openaire +2 more sources