Results 131 to 140 of about 712,315 (261)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Medical genetics needs assessment: An online cross-sectional survey from Nepal. [PDF]

Genet Med Open
Gyawali P, Shrestha B, Beharry K, Agarwal G, Quinonez SC.   +4 more
europepmc   +1 more source

Elivaldogene autotemcel approved for treatment of cerebral adrenoleukodystrophy (CALD) in males: A therapeutics bulletin of the American College of Medical Genetics and Genomics (ACMG). [PDF]

Genet Med Open, 2023
Scott AI, Mallhi KK, Ganesh J, Chen WL, ACMG Therapeutics Committee8∗documents@acmg.net.   +4 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The Evolving Role of Artificial Intelligence in Medical Genetics: Advancing Healthcare, Research, and Biosafety Management. [PDF]

Genes (Basel)
Wu YC, Tuo N, Shi G, Li K, Song Z, Li Y.
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Integration of medical genetics and genomics into faculty development programs in india: assessment of success and experience of genetic research centre. [PDF]

J Community Genet
Joseph S, Minde N, Babu S, Gawde H, Naik C, Bhanothu V, Sudhakar D, Bharankar J, Agarbattiwala T, Kumar A, Sachdeva G, Mahale SD, Pande S.   +12 more
europepmc   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Strengthening Medical Genetics and Genomic Medicine in Colombia: Progress, Challenges, and Strategic Opportunities. [PDF]

J Community Genet
Rojas PLP, Mora LM, Rincón JS, Montoya IZ, León-Sanabria MC, Urueña-Serrano AM.   +5 more
europepmc   +1 more source

Disrupting Essentialism in Medical Genetics Education. [PDF]

Med Sci Educ, 2022
Gingell G, Bergemann AD.
europepmc   +1 more source