Results 101 to 110 of about 12,776,841 (339)
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
BMC Health Services Research, 2012 BackgroundMany critical treatment decisions are based on the medical history of patients with an acute coronary syndrome (ACS). Discrepancies between the medical history documented by a health professional and the patient's own report may therefore have ...
Chete M. Eze-Nliam +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
DeepCare: A Deep Dynamic Memory Model for Predictive Medicine
, 2016 Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies.
A Graves +13 more
core +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Tuberkulose: Kampen mot bekjempelsen
Heimen, 2019 Traditionally, the turning point in the fight against tuberculosis is perceived as Robert Koch’s description of the bacterium in 1882. In Norway, the legislation from 1900 has been interpreted as a breakthrough.
Ole Georg Moseng
doaj +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Journal of Client-centered Nursing Care, 2020 Background: Considering the new Coronavirus outbreak and limited data about this pandemic in Iran, this study aimed at assessing the demographic characteristics, clinical symptoms, paraclinical findings, and radiological features of hospitalized patients
Abdollah Abolfathi +5 more
doaj
Indian Journal of Endocrinology and Metabolism, 2015 Mountford Joseph Bramley was one of the educationists whose sincere efforts are undeniable in the making of modern India. After achieving the Member of the Royal College of Surgeons diploma, he joined the Malta Garrison as a Hospital Assistant and was ...
Subhankar Chatterjee +2 more
doaj +1 more source