Results 121 to 130 of about 10,322,069 (330)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Parasites and plantations: Disease, environment and society in efforts to induce extinction of hookworm in Jamaica, 1919–1936

open access: yesCambridge Prisms: Extinction
Studies of extinction typically focus on unintended losses of biodiversity and culture. This study, however, examines an attempt to induce extinction of a parasite: human hookworm (Necator americanus and Ancylostoma duodenale).
Jonathan D. Roberts   +4 more
doaj   +1 more source

ESSAY ON THE HISTORY OF THE DEPARTMENT OF GENERAL AND MEDICAL CHEMISTRY NAMED AFTER PROF. V.V. KHORUNZHIY

open access: diamond, 2023
З. М. Саркисян   +5 more
openalex   +2 more sources

The autonomic medical history

open access: yesClinical Autonomic Research, 2017
D. Goldstein, W. Cheshire
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Competing‐risks model in screening for pre‐eclampsia in twin pregnancy by maternal characteristics and medical history

open access: yesUltrasound in Obstetrics and Gynecology, 2017
Carla Francisco   +4 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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