Results 151 to 160 of about 2,275,397 (311)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats. [PDF]

open access: yesNat Commun
Steinfeldt J   +12 more
europepmc   +2 more sources

Editorial: 50 years of BMT: risk stratification, donor matching and stem cell collection for transplantation

open access: yesFrontiers in Oncology, 2023
Nelson Hamerschlak   +2 more
doaj   +1 more source

A smartphone app for preschool wheezing and reliability of medical history collection. [PDF]

open access: yesItal J Pediatr
Ullmann N   +7 more
europepmc   +1 more source

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