Results 161 to 170 of about 4,852,263 (336)
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga+8 more
wiley +1 more source
The long history of medical migration to the united Kingdom is relatively well known. however, until recently the story of the contribu-tion of South Asian doctors to specific fields has been less discussed.
Bornat, Joanna+2 more
core
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy+9 more
wiley +1 more source
THE MEDICAL HISTORY OF CHRISTOPHER COLUMBUS,AND THE PART TAKEN BY THE MEDICAL PROFESSION IN THE DISCOVERY OF AMERICA. Read by the Author before the Section on General Medicine of the First Pan-American Medical Congress, Washington, D. C., Sept. 7, 1893. [PDF]
A. M. Fernandez de Ybarra
openalex +1 more source
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin+10 more
wiley +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla+15 more
wiley +1 more source
The medical and surgical history of the war of the rebellion
Joseph K. Barnes
openalex +1 more source