Results 221 to 230 of about 10,322,069 (330)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats. [PDF]

Nat Commun
Steinfeldt J, Wild B, Buergel T, Pietzner M, Upmeier Zu Belzen J, Vauvelle A, Hegselmann S, Denaxas S, Hemingway H, Langenberg C, Landmesser U, Deanfield J, Eils R.   +12 more
europepmc   +2 more sources

An Effective Teaching Method to Enhance History-Taking Skills for Chinese Medical Students

, 2018
Si-Min Huang, Peng Xu, Lie Feng, Chunting Lu, Jing Yang   +4 more
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Pioneering Physician: Dr. Elizabeth Blackwell and the Path to Medical History. [PDF]

Cureus
Thakur J, Choudhari SG, Gaidhane A.
europepmc   +1 more source

An epidemiological study of hand eczema. III. Characterization of hairdressers with and without hand eczema, regarding demographic factors and medical histories

, 1994
Jan-Øyvind Holm, Marit B. Veierød
openalex   +2 more sources

Role of medical history and medication use in the aetiology of upper aerodigestive tract cancers in Europe: the ARCAGE study.

Annals of Oncology, 2012
Tatiana V. Macfarlane, Gary J. Macfarlane, N. Thakker, Simone Benhamou, Christine Bouchardy, Wolfgang Ahrens, H. Pohlabeln, P. Lagiou, A. Lagiou, A. Lagiou, X. Castellsagué, A. Agudo, A. Slámová, Jan Plzák, Franco Merletti, L. Richiardi, Renato Talamini, L. Barzan, K. Kjaerheim, Cristina Canova, Lorenzo Simonato, David I. Conway, P. McKinney, Peter Thomson, Philip Sloan, A. Znaor, Claire M. Healy, B. McCartan, M. Marron, P. Brennan   +29 more
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

La syphilis à son crépuscule. Déplacements d’énergies érotico-morbides dans quelques destins romanesques, entre Europe et Amérique, à l’aube de la révolution antibiotique (Zweig, Mann, Miller, Nin, Serpa)

Revue des Sciences Humaines
Yves Schulze
doaj   +1 more source

The battle to save the anus: a triumph of careful colonoscopy and medical history taking. [PDF]

Endoscopy
Shou H, Fan L, Liu X, Cai XL, Zhou PH.
europepmc   +1 more source