Results 41 to 50 of about 4,852,263 (336)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Children’s psychiatric medical history. Review

open access: yesEuropean Psychiatry, 2021
Introduction The prevalence of mental disorders in children and adolescents varies between 5 and 22%, depending on the methodology, type of interview, samples and inclusion of the disability criterion.
M.O. Solis   +4 more
doaj   +1 more source

Semantic Integration of Cervical Cancer Data Repositories to Facilitate Multicenter Association Studies: The ASSIST Approach [PDF]

open access: yes, 2009
The current work addresses the unifi cation of Electronic Health Records related to cervical cancer into a single medical knowledge source, in the context of the EU-funded ASSIST research project.
Agorastos, Theodoros   +8 more
core   +2 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Design of a wireless patient diagnosis system [PDF]

open access: yes, 2012
Medical administrative and diagnosis procedures require the retrieval of patient diagnosis history before treatments and drug administration. This involves careful checking of the patient past record which might be stored electronically or in paper ...
Holmes, Violeta, Jimoh, F.
core  

Halting the 'sad degenerationist parade': medical concerns about heredity and racial degeneracy in New Zealand psychiatry, 1853-99. [PDF]

open access: yes, 2012
Historians have focused on early twentieth-century positive eugenics in New Zealand. In this article, I argue that the response came from a tradition of concern about heredity and white racial degeneracy, which extended beyond the British Empire.
Dawson, Mark
core   +2 more sources

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

La cesión de datos de salud fuera del ámbito sanitario. Análisis de supuestos concretos en que la información sanitaria se transmite para el cumplimiento de fines distintos al de la protección de la salud de las personas*

open access: yesRevista Vasca de Administración Pública, 2011
The most common way of transfer of health data is the assignment or communication of data. Leaving aside those cases where data are transfered within a strictly confined health care sphere, the data on health can be transfered beyond that area.
Unai Aberasturi Gorriño   +1 more
doaj   +1 more source

Medical use of cannabis: italian and european legislation [PDF]

open access: yes, 2018
This review illustrates some brief considerations of the medical use of cannabis recently issued in Italy. History and uses of cannabis throughout centuries and different countries are illustrated together with a description of botany and active ...
Di Luca, A.   +3 more
core   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

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