Results 41 to 50 of about 2,275,397 (311)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Communication pitfalls of traditional history and physical write-up documentation
Advances in Medical Education and Practice, 2016 Jeffrey L Brown1,2 1Department of Pediatrics, New York Medical College, 2Departments of Pediatrics and Psychiatry, Weill Cornell Medical College, NY, USA Background: An unofficial standardized “write-up” outline is commonly used for ...
Brown JL
doaj
Revista Vasca de Administración Pública, 2011 The most common way of transfer of health data is the assignment or communication of data. Leaving aside those cases where data are transfered within a strictly confined health care sphere, the data on health can be transfered beyond that area.
Unai Aberasturi Gorriño +1 more
doaj +1 more source
The implication of integrated training program for medical history education
Biomedical Journal, 2015 Background: A full spectrum of medical education requires not only clinical skills but also humanistic qualities in the medical professionals, which can be facilitated by an integrated training program.
Shun-Sheng Chen, Peiyi Chou
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The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
History of Islamic Medical Schools in Turkey"s Territory
Balkan Medical Journal, 2020 In today’s political borders of the Republic of Turkey, there exist very old institutions that train physicians according to Islamic medical science. In this study, 19 health institutions whose locations have been determined and documents finalized were ...
Selman Çıkmaz, Recep Mesut
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FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Tıp Tarihyazımı: Karşıtlıklar, Etkileşimler
Osmanli Bilimi Arastirmalari, 2020 Bu makalenin amacı, on dokuzuncu ve yirminci yüzyıllarda Batı Avrupa ve Amerika Birleşik Devletleri’nde tıp tarihçiliğinin temel aşamalarına genel bir bakış sunmaktır. Makale, klasik olarak tanımlanan ve öncelikle hekimler tarafından kaleme alınan klinik
Ceren Gülser İli̇kan Rasi̇moğlu
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Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source