Results 51 to 60 of about 2,275,397 (311)

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

Joint effect of modifiable risk factors on Parkinson’s disease: a large-scale longitudinal study

Frontiers in Human Neuroscience
IntroductionPrevious researches have often underestimated the diversity and combined effects of risk factors for Parkinson’s disease (PD). This study aimed to identify how multiple modifiable risk factors collectively impact PD.MethodsThe study included ...
Panlong Li, Xirui Zhu, Min Liu, Yanfeng Wang, Chun Huang, Junwei Sun, Shan Tian, Yuna Li, Yuan Qiao, Junting Yang, Shanshan Cao, Chaohua Cong, Lei Zhao, Jingjing Su, Dandan Tian   +14 more
doaj   +1 more source

Acute Lymphatic Filariasis Infection in United States Armed Forces Personnel Deployed to the Pacific Area of Operations during World War II Provides Important Lessons for Today

Tropical Medicine and Infectious Disease, 2020
The deployment of United States (US) Armed Forces personnel into the central Pacific islands of Samoa and Tonga, which is highly-endemic for lymphatic filariasis (LF), resulted in thousands of cases of the acute form of this disease and greatly reduced ...
Wayne D. Melrose, Peter A. Leggat
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Medical History in Korean History Textbooks [PDF]

Uisahak, 2004
This thesis is a research how the medical history described and organized in the Korean history textbook to compare the 7th educational program from 2002 to the 6th educational program from 1994-2001 in Korea.
KO Il-Young, CHU Chin-Oh
doaj  

Family Medical History [PDF]

Academic Emergency Medicine, 2017
“Is there a family history?” As I stood there watching her cry from pain and fear, that question shattered my soul like a bullet entering a thorax. “Yes, there is a family history. A strong one.” This article is protected by copyright. All rights reserved.
openaire   +3 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Considering pandemics, history, and ethics

Sjuttonhundratal, 2022
Elina Maaniitty
doaj   +1 more source

Tıp Tarihi Açısından Doktor Milaslı İsmail Hakkı’nın Veremle İlgili Görüşleri

Lokman Hekim Dergisi
Amaç: Bu yazının amacı, geç Osmanlı ve erken Cumhuriyet Dönemi aydınlarından Doktor Milaslı İsmail Hakkı’nın bilim tarihi ve sağlık alanındaki katkılarını değerlendirmektir.
Nusret Gedik, Fatoş Öksüzaşıkı
doaj   +1 more source

Mountford Joseph Bramley: A pioneering thyroidologist and the first principal of Asia′s oldest medical college

Indian Journal of Endocrinology and Metabolism, 2015
Mountford Joseph Bramley was one of the educationists whose sincere efforts are undeniable in the making of modern India. After achieving the Member of the Royal College of Surgeons diploma, he joined the Malta Garrison as a Hospital Assistant and was ...
Subhankar Chatterjee, Adrija Datta, Pranab Chatterjee   +2 more
doaj   +1 more source