Results 71 to 80 of about 10,322,069 (330)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

A Generative Pretrained Transformer (GPT)–Powered Chatbot as a Simulated Patient to Practice History Taking: Prospective, Mixed Methods Study

open access: yesJMIR Medical Education
Background Communication is a core competency of medical professionals and of utmost importance for patient safety. Although medical curricula emphasize communication training, traditional formats, such as real or simulated patient interactions, can ...
F. Holderried   +9 more
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

A Language Model–Powered Simulated Patient With Automated Feedback for History Taking: Prospective Study

open access: yesJMIR Medical Education
Background Although history taking is fundamental for diagnosing medical conditions, teaching and providing feedback on the skill can be challenging due to resource constraints.
F. Holderried   +6 more
semanticscholar   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Intelligent Prediction of Human Health Risks Based on Medical History: A Review [PDF]

open access: yesAl-Rafidain Journal of Computer Sciences and Mathematics
The main access to modern healthcare using artificial technologies is related to the medical topic and prediction of risks to human health. Enhance patient medical care using intelligent prediction models such as machine learning, like gradient boosting ...
Mais Irreem kamal, Fawziya Ramo
doaj   +1 more source

Discrepancies between the medical record and the reports of patients with acute coronary syndrome regarding important aspects of the medical history

open access: yesBMC Health Services Research, 2012
BackgroundMany critical treatment decisions are based on the medical history of patients with an acute coronary syndrome (ACS). Discrepancies between the medical history documented by a health professional and the patient's own report may therefore have ...
Chete M. Eze-Nliam   +7 more
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Communication pitfalls of traditional history and physical write-up documentation

open access: yesAdvances in Medical Education and Practice, 2016
Jeffrey L Brown1,2 1Department of Pediatrics, New York Medical College, 2Departments of Pediatrics and Psychiatry, Weill Cornell Medical College, NY, USA Background: An unofficial standardized “write-up” outline is commonly used for ...
Brown JL
doaj  

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