Results 71 to 80 of about 4,852,263 (336)
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Medical College of Virginia Hospitals 125 Years of health care 1861 - 1986 [PDF]
, 1986 The Medical College of Virginia (MCV) grew in size and reputation in the latter half of the twentieth century, amid a time of technological advancements in the medical field and the rise of teaching hospitals.
McGuire, Hunter H.
core +1 more source
DeepCare: A Deep Dynamic Memory Model for Predictive Medicine
, 2016 Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies.
A Graves +13 more
core +1 more source
Health and place in historical perspective: medicine, ethnicity, and colonial identities [PDF]
, 2012 Introduction to special issue. This Special Issue includes articles first presented as papers at a two-day symposium held at the University of Waikato, New Zealand, in February 2011. The event was designed to highlight a large Royal Society of New Zealand
Coleborne, Catharine, McCarthy, Angela
core +2 more sources
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Медицинский вестник Юга России, 2013 Purpose: To study peculiarities of the clinical profile of patients of reproductive age suffering from external genital endometriosis (EGE).Materials and methods: Analysis of clinical presentations of the disease and laboratory examination in 96 patients
K. V. Slesareva +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Risk factors for acute exacerbations of COPD in a primary care population: A retrospective observational cohort study [PDF]
, 2014 Objectives: To evaluate risk factors associated with exacerbation frequency in primary care. Information on exacerbations of chronic obstructive pulmonary disease (COPD) has mainly been generated by secondary care-based clinical cohorts.
Hawkins, A +3 more
core +3 more sources
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source