Results 81 to 90 of about 4,852,263 (336)

Joint effect of modifiable risk factors on Parkinson’s disease: a large-scale longitudinal study

open access: yesFrontiers in Human Neuroscience
IntroductionPrevious researches have often underestimated the diversity and combined effects of risk factors for Parkinson’s disease (PD). This study aimed to identify how multiple modifiable risk factors collectively impact PD.MethodsThe study included ...
Panlong Li   +14 more
doaj   +1 more source

Risks and Risk Factors of Repeated Suicidal Attempt: Study of Unconscious Poisoned Patients [PDF]

open access: yes
Introduction: Most drug overdoses are due to suicidal attempts. This study was designed to analyze the risks and risk factors of poisoned patients with repeated suicidal attempt in Iran.
فرزانه, اسماعیل   +1 more
core  

A culture of silence: modes of objectification and the silencing of disabled bodies [PDF]

open access: yes, 2015
Throughout history different practices have attempted to silence the experiences of disabled people. In this paper we explore some of these practices including the medical, familial, and self-subjugating practices English-speaking Canadian polio ...
Fady Shanouda   +13 more
core   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

A review of medical conditions of patients attending dental clinics in Saudi Arabia

open access: yesSaudi Journal for Health Sciences
This review aimed to identify the most common medical conditions of patients attending dental clinics in Saudi Arabia by conducting a comprehensive search of electronic databases including PubMed, Web of Science, ScienceDirect, Scopus, and Wiley Online ...
Khalid Aljohani   +3 more
doaj   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Development of Physics Applied to Medicine in the UK, 1945–90 [PDF]

open access: yes, 2006
Annotated and edited transcript of a Witness Seminar held on 5 July 2005. Introduction by Dr Jeff Hughes.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2006.©The Trustee of the Wellcome Trust, London, 2006.All volumes ...
Christie, DA, Tansey, EM
core  

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

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