Results 81 to 90 of about 10,322,069 (330)

The implication of integrated training program for medical history education

Biomedical Journal, 2015
Background: A full spectrum of medical education requires not only clinical skills but also humanistic qualities in the medical professionals, which can be facilitated by an integrated training program.
Shun-Sheng Chen, Peiyi Chou
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The First Medical Text in Preventive Medicine Written in Islamic World

Journal of Research on History of Medicine, 2014
Medical books written in Islamic societies have devoted special chapters to preventive medicine named Hefzossehha’. Nowadays, Ferdous Alhekmah is considered as the first medical text authored by Muslim scientists in Islamic countries.
Seied Saeid Esmaeili, Gholamreza Noormohammadi, Faramarz Fallahi, Seyed Hamid Kamali   +3 more
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Between Air and Artery: A History of Cardiopulmonary Bypass and the Rise of Modern Cardiac Surgery

Journal of Cardiovascular Development and Disease
Cardiopulmonary bypass (CPB) is one of the most groundbreaking medical innovations in history, enabling safe and effective heart surgery by temporarily replacing the function of the heart and lungs.
Vasileios Leivaditis, Andreas Maniatopoulos, Francesk Mulita, Paraskevi Katsakiori, Nikolaos G. Baikoussis, Sofoklis Mitsos, Elias Liolis, Vasiliki Garantzioti, Konstantinos Tasios, Panagiotis Leventis, Nikolaos Kornaros, Andreas Antzoulas, Dimitrios Litsas, Levan Tchabashvili, Konstantinos Nikolakopoulos, Manfred Dahm   +15 more
doaj   +1 more source

The Relationship between Students’ Probationary History, Failure to Follow Career Counseling and Entry into the Supplemental Offer Acceptance Program (SOAP): A Comparison between Two Medical Schools [PDF]

, 2017
Scott Cottrell, Julie Phillips, Jason S. Hedrick, Linda S. Nield, Jeffrey A. Vos, Brian Mavis, Norman D. Ferrari   +6 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Sickle cell disease: suspect, check, diagnose—practical tips for non-SCD experts to suspect and diagnose SCD in low-prevalence European settings

Frontiers in Medicine
Sickle cell disease (SCD) is the most common monogenic disorder, including a group of autosomal recessive hemoglobinopathies characterized by hemoglobin polymerization and sickling of red blood cells when low oxygen concentrations are present.
Giovanni Palazzi, Silvia Benemei, Cristiano Gallucci, Francesco Arcioni, Silverio Perrotta   +4 more
doaj   +1 more source