Results 91 to 100 of about 648,180 (293)

Challenging history taking encounters: a systematic review

open access: yes, 2020
Even when armed with good generic communication skills, all physicians will encounter challenging history taking encounters. Experienced clinicians, particularly those with a focus on clinical settings that present specific challenges (e.g. assessment of
Jing Sun   +9 more
core   +1 more source

An Islamic Model for Taking Patients' Spiritual History: Islamic Model of Taking Spiritual History

open access: yes, 2021
Background and Aim: In recent years, the spiritual dimension of human nature has received ever-increasing attention for better healthcare. One way of responding to this issue is taking the patients’ spiritual history in a healthcare setting.
Ghaempanah , Zeinab   +3 more
core   +1 more source

Deficiencies of history taking among medical students

open access: yesSaudi Medical Journal, 2002
This study was designed to identify the deficiencies of the history taken by final medical students at the University of Bahr Elghazal, Khartoum, Sudan, during the academic year 2000 through to 2001.Throughout the academic year the author observed the students while taking history. Each student was asked to give a fully written case history. I assessed
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

학질에서 말라리아로: 한국 근대 말라리아의 역사(1876-1945) [PDF]

open access: yes, 2011
Although it is not certain when malaria began to appear in Korea, malaria is believed to have been an endemic disease from ancient times. It was Dr. H. N.
여인석
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Can a Modified Medical History Performed (in a Virtual Setting) by Medical Students Provide a More Efficient and Accurate History? [PDF]

open access: yes, 2022
Learning Objectives: To determine whether a history elicited by using an modified format of questions, i.e. past medical history prior to history of present illness, can reduce the amount of time necessary to obtain vital historical elements compared to ...
Cuadra, Kristen   +4 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Knowledge-Based Chatbots in Clinical Teaching: AI-Powered Virtual Patients to Improve History-Taking During Internal Medicine Rotations

open access: yesInternational Medical Education
Proficiency in history-taking is foundational to safe clinical practice, yet traditional teaching methods offer infrequent opportunities for deliberate practice.
Shayma Aljedaani   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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