Results 81 to 90 of about 1,824,761 (332)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

Could a neurological disease be a part of Mozart’s pathography? [Neurološki aspekt Mozartove patografije] [PDF]

, 2011
As expected, since we recently celebrated the 250th anniversary of birth of Wolfgang Amadeus Mozart, there has been again a renewal of interest in his short but intensive life, as well as in the true reason of his untimely dead.
Erdeljić, Viktorija, Ivkić, Goran
core  

Significance of experts' overall ratings for medical student competence in relation to history-taking

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Overall ratings (ORs) of competence, given by expert physicians, are increasingly used in clinical skills assessments. Nevertheless, the influence of specific components of competence on ORs is incompletely understood. The aim here
Luiz Ernesto de Almeida Troncon
doaj   +1 more source

Profile of patients attended in the Exam and Screening Sector of the Dentistry Faculty of Universidade de Passo Fundo, Rio Grande do Sul, Brazil [PDF]

RGO: Revista Gaúcha de Odontologia, 2009
Objectives: The aim of this study is to describe the systemic diseases and dental treatment needs that most frequently affect the population of Passo Fundo, Rio Grande do Sul, Brazil and region, in patients attended at the Examination, Urgency and ...
Daiane Amarante de Mattos, Adriane Lehnen, Micheline Sandini Trentin, Soluete Oliveira da Silva, João Paulo de Carli, Maria Salete Sandini Linden   +5 more
doaj  

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Dialogue-Contextualized Re-ranking for Medical History-Taking

, 2023
AI-driven medical history-taking is an important component in symptom checking, automated patient intake, triage, and other AI virtual care applications. As history-taking is extremely varied, machine learning models require a significant amount of data to train.
Zhu, Jian, Valmianski, Ilya, Kannan, Anitha   +2 more
openaire   +2 more sources

An Educational Tool for Teaching Medication History Taking to Pharmacy Students [PDF]

American Journal of Pharmaceutical Education, 2013
To implement and evaluate the use of a situated-learning experience to prepare second-year pharmacy students to conduct medication history interviews in preparation for introductory pharmacy practice experiences (IPPE) at ambulatory clinic sites.Second-year doctor of pharmacy (PharmD) students (n=200) used the Medication Mysteries Infinite Case Tool, a
Sando, Karen R., Elliott, Jennifer, Stanton, Melonie L., Doty, Randell   +3 more
openaire   +3 more sources

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Willingness and attitudes of the general public towards the involvement of medical students in their healthcare [PDF]

, 2012
Objectives: To determine if patients allow medical students to perform less invasive procedures compared to more invasive procedures, and how this is related to patient demographics and previous experience with medical students.
Abu Jubain, Mariam, Alobaidi, Hajar, Bholah, Sanah, Kanani, Farah, Koghar, Raveen, Shereef, Hannah, Sitch, Alice   +6 more
core   +3 more sources