Results 101 to 110 of about 752,995 (286)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

An Analysis of Visual Narrative in the Medical Manuscript “Lazzat Un Nisa’” [PDF]

open access: yesJournal of Research on History of Medicine
Most people believe that they are adequately aware of sex and its etiquette and hence, they don’t need any education to improve their sexual knowledge. However, relevant issues that are often treatable, like sexual diseases or dissatisfaction, have made ...
Leila Rezaeian, Fahimeh Zarezadeh
doaj  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

On the History of Creation of the Atlas of Tibetan Medicine (17th century): source aspects

open access: yesМонголоведение
Introduction. The article examines the history of the creation of the set of illustrations the Atlas of Tibetan Medicine (also known as Tibetan Medical Paintings) by Desi Sangye Gyatso (1653–1705) to his Vaiḍūrya sngon po, which is a drudrel (‘bru ‘grel)
Yumzhana Zh. Zhabon
doaj   +1 more source

Cinchona amazonica Standl. (Rubiaceae) in the state of Acre, Brazil [PDF]

open access: yesBoletim do Museu Paraense Emílio Goeldi. Ciências Naturais, 2006
The present research is about dendrology, geographic distribution and status of conservation of Cinchona amazonica Standl. with are plants with medical interest; they grow in the state of Acre, Brazil.
Percy Amilcar Zevallos Pollito   +1 more
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Comparison of two 3D scanning software to identify facial features: a prospective instrument to predict difficult airway

open access: yesPerioperative Medicine
Background Clinical airway assessment has limited predictive ability to anticipate difficult airway. Three-dimensional (3D) technologies have emerged in medicine as valuable tools in different settings including innovation and surgical planning.
Alexander Rocuts   +6 more
doaj   +1 more source

Research on Test Method of Active Medical Device Preset Service Life Evaluation

open access: yesZhongguo yiliao qixie zazhi
When applying for registration of an active medical device, it is necessary to submit research and verification data regarding the device's service life.
Fei HE, Weiming WANG
doaj   +1 more source

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