Results 111 to 120 of about 755,073 (284)
3D printing of an optic pathway model from 7T MRI for education
3D Printing in MedicineBackground The optic pathway is a complex neural structure responsible for transmitting visual information from the retina to the brain. Traditionally, the optic pathway has been depicted using two-dimensional (2D) illustrations, which, while useful for ...
Jack A. Black +6 more
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
An Analysis of Visual Narrative in the Medical Manuscript “Lazzat Un Nisa’” [PDF]
Journal of Research on History of MedicineMost people believe that they are adequately aware of sex and its etiquette and hence, they don’t need any education to improve their sexual knowledge. However, relevant issues that are often treatable, like sexual diseases or dissatisfaction, have made ...
Leila Rezaeian, Fahimeh Zarezadeh
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
On the History of Creation of the Atlas of Tibetan Medicine (17th century): source aspects
МонголоведениеIntroduction. The article examines the history of the creation of the set of illustrations the Atlas of Tibetan Medicine (also known as Tibetan Medical Paintings) by Desi Sangye Gyatso (1653–1705) to his Vaiḍūrya sngon po, which is a drudrel (‘bru ‘grel)
Yumzhana Zh. Zhabon
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Cinchona amazonica Standl. (Rubiaceae) in the state of Acre, Brazil [PDF]
Boletim do Museu Paraense Emílio Goeldi. Ciências Naturais, 2006 The present research is about dendrology, geographic distribution and status of conservation of Cinchona amazonica Standl. with are plants with medical interest; they grow in the state of Acre, Brazil.
Percy Amilcar Zevallos Pollito +1 more
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Perioperative MedicineBackground Clinical airway assessment has limited predictive ability to anticipate difficult airway. Three-dimensional (3D) technologies have emerged in medicine as valuable tools in different settings including innovation and surgical planning.
Alexander Rocuts +6 more
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Research on Test Method of Active Medical Device Preset Service Life Evaluation
Zhongguo yiliao qixie zazhiWhen applying for registration of an active medical device, it is necessary to submit research and verification data regarding the device's service life.
Fei HE, Weiming WANG
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