Results 131 to 140 of about 755,073 (284)

Curriculum semi-supervised segmentation

open access: yes, 2019
This study investigates a curriculum-style strategy for semi-supervised CNN segmentation, which devises a regression network to learn image-level information such as the size of a target region.
Ayed, Ismail Ben   +3 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Déplier le dispositif. La mobilité du chercheur comme ressource pour l’étude de l’expertise médico-légale

open access: yesSociologies, 2017
This article proposes to explore the notion of apparatus as an invitation for researchers to embrace a moving research approach. It constitutes an illustration of this proposition threw our research on medico-legal expertise.
Romain Juston
doaj  

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

MEDICAL ILLUSTRATION

open access: yesInternational Journal of Clinical Practice, 1953
openaire   +3 more sources

cts : An R Package for Continuous Time Autoregressive Models via Kalman Filter

open access: yesJournal of Statistical Software, 2013
We describe an R package cts for fitting a modified form of continuous time autoregressive model, which can be particularly useful with unequally sampled time series. The estimation is based on the application of the Kalman filter. The paper provides the
Zhu Wang
doaj  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Effective learning environments – the process of creating and maintaining an online continuing education tool

open access: yesAdvances in Medical Education and Practice, 2017
Sharon Davies,1 Gianni Roberto Lorello,2 Kristi Downey,1 Zeev Friedman1 1Department of Anesthesia, Sinai Health System, University of Toronto, Toronto, ON, Canada; 2Department of Anesthesia, Sunnybrook Health Sciences Centre, University of Toronto ...
Davies S   +3 more
doaj  

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