Results 121 to 130 of about 492,068 (301)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Correction to: Primary health information standard system based on semantic interoperability
BMC Medical Informatics and Decision Making, 2019 After publication of this supplement article [1], it was brought to our attention that the first and correspondence authors’ affiliation information was incorrectly spelt. The original spelling was written as ‘Sothern’.
Xia Zhao +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Computational Algorithms on Medical Image Processing
Current Medical Imaging Formerly Current Medical Imaging Reviews, 2020 openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 2004 Relevance feedback has gained much interest from researchers in the discipline of content-based image retrieval (CBIR). However, such approach is rarely used in the content-based medical image retrieval (CBMIR) systems.
Fung, C.C., Chung, K.P.
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Active contours with weighted external forces for medical image segmentation [PDF]
Parametric active contours have been widely used for image segmentation. However, high noise levels and weak edges are the most acute issues that hinder their performance, particularly in medical images.
Khadidos, Alaa +2 more
core
A brief introduction to medical image processing, designing and 3D printing for orthopedic surgeons. [PDF]
Jt Dis Relat Surg, 2023 Bahadır B +3 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source