Results 131 to 140 of about 492,068 (301)

Simple post-processing of medical images

open access: yesYonsei Medical Journal, 1995
Most of medical images, especially tomographic images, are in digital. It is worth getting these digital data onto the personal computer and doing extra post-processing without much difficulties. The extra processing of obtained medical images may not give the great benefits for clinical purpose, however it is recommended to analyze obtained images ...
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Low rank based FAZ segmentation in OCTA images

open access: yesScientific Reports
Optical Coherence Tomography Angiography (OCTA) is a non-invasive method for vascular imaging of different tissues. Several diseases can disturb the blood supplying of retinal tissues which leads to loss of blood vessels and a reduction in the vascular ...
Farnaz Sedighin   +2 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Directional edge and texture representations for image processing [PDF]

open access: yes, 2007
An efficient representation for natural images is of fundamental importance in image processing and analysis. The commonly used separable transforms such as wavelets axe not best suited for images due to their inability to exploit directional ...
Yao, Zhen
core  

Transmantle pressure under the influence of free breathing: non-invasive quantification of the aqueduct pressure gradient in healthy adults

open access: yesFluids and Barriers of the CNS
Background The pressure gradient between the ventricles and the subarachnoid space (transmantle pressure) is crucial for understanding CSF circulation and the pathogenesis of certain neurodegenerative diseases.
Pan Liu   +5 more
doaj   +1 more source

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