Results 111 to 120 of about 169,019 (308)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Brain tumor segmentation based on a hybrid clustering technique
Egyptian Informatics Journal, 2015 Image segmentation refers to the process of partitioning an image into mutually exclusive regions. It can be considered as the most essential and crucial process for facilitating the delineation, characterization, and visualization of regions of interest
Eman Abdel-Maksoud +2 more
doaj +1 more source
From uncertainty to adaptivity : multiscale edge detection and image segmentation [PDF]
This thesis presents the research on two different tasks in computer vision: edge detection and image segmentation (including texture segmentation and motion field segmentation).
Liang, Kung-Hao
core
Toward automated evaluation of interactive segmentation [PDF]
, 2011 We previously described a system for evaluating interactive segmentation by means of user experiments (McGuinness and O’Connor, 2010). This method, while effective, is time-consuming and labor-intensive.
McGuinness, Kevin +4 more
core +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Medical Image Segmentation by Water Flow
, 2007 We present a new image segmentation technique based on the paradigm of water flow and apply it to medical images. The force field analogy is used to implement the major water flow attributes like water pressure, surface tension and adhesion so that the ...
Nixon, Mark, Liu, Xin
core
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Medical Image Segmentation: A Comprehensive Review of Deep Learning-Based Methods
TomographyMedical image segmentation is a critical application of computer vision in the analysis of medical images. Its primary objective is to isolate regions of interest in medical images from the background, thereby assisting clinicians in accurately ...
Yuxiao Gao +5 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source