Results 101 to 110 of about 16,791,752 (293)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Performance characterization of clustering algorithms for colour image segmentation [PDF]

open access: yes, 2006
This paper details the implementation of three traditional clustering techniques (K-Means clustering, Fuzzy C-Means clustering and Adaptive K-Means clustering) that are applied to extract the colour information that is used in the image segmentation ...
Ilea, Dana E.   +2 more
core   +2 more sources

Block-based Against Segmentation-based Texture Image Retrieval

open access: yes, 2010
This paper concerns the best approach to the capture of local texture features for use in content-based image retrieval (CBIR) applications. From our previous work, two approaches have been suggested, the multiscale block-based approach and the automatic
Lewis, Paul   +3 more
core   +2 more sources

BRAIN MR IMAGE SEGMENTATION BY MODIFIED ACTIVE CONTOURS AND CONTOURLET TRANSFORM

open access: yesICTACT Journal on Image and Video Processing, 2017
Multiresolution analysis is often used for image representation and processing because it can represent image at the split resolution and scale space.
P Nageswara Reddy   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Unsupervised colour image segmentation using dual-tree complex wavelet transform [PDF]

open access: yes, 2010
In this paper we present an effective unsupervised colour image segmentation algorithm which uses multiscale edge information and spatial colour content. The multiscale edge information is extracted using the dual-tree complex wavelet transform.
Tjahjadi, Tardi, Çelik, Turgay
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Medical Image Segmentation: A Comprehensive Review of Deep Learning-Based Methods

open access: yesTomography
Medical image segmentation is a critical application of computer vision in the analysis of medical images. Its primary objective is to isolate regions of interest in medical images from the background, thereby assisting clinicians in accurately ...
Yuxiao Gao   +5 more
doaj   +1 more source

Brain tumor segmentation based on a hybrid clustering technique

open access: yesEgyptian Informatics Journal, 2015
Image segmentation refers to the process of partitioning an image into mutually exclusive regions. It can be considered as the most essential and crucial process for facilitating the delineation, characterization, and visualization of regions of interest
Eman Abdel-Maksoud   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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