Results 101 to 110 of about 169,019 (308)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Multimodal Evaluation for Medical Image Segmentation [PDF]

open access: yes, 2007
This paper is a joint effort between five institutions that introduces several novel similarity measures and combines them to carry out a multimodal segmentation evaluation. The new similarity measures proposed are based on the location and the intensity values of the misclassified voxels as well as on the connectivity and the boundaries of the ...
Rubén Cárdenes   +7 more
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Medical Image Segmentation

open access: yesInternational Research Journal on Advanced Engineering Hub (IRJAEH)
Medical image segmentation is a critical component in the development of computer-aided diagnosis and treatment planning systems. This paper provides a comprehensive survey of recent advances in segmentation techniques applied to various imaging modalities, including Magnetic Resonance Imaging (MRI).
null Arpit Mohankar   +4 more
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Advances in Medical Image Segmentation: A Comprehensive Review of Traditional, Deep Learning and Hybrid Approaches

open access: yesBioengineering
Medical image segmentation plays a critical role in accurate diagnosis and treatment planning, enabling precise analysis across a wide range of clinical tasks. This review begins by offering a comprehensive overview of traditional segmentation techniques,
Yan Xu   +5 more
doaj   +1 more source

BRAIN MR IMAGE SEGMENTATION BY MODIFIED ACTIVE CONTOURS AND CONTOURLET TRANSFORM

open access: yesICTACT Journal on Image and Video Processing, 2017
Multiresolution analysis is often used for image representation and processing because it can represent image at the split resolution and scale space.
P Nageswara Reddy   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Management Information Services for Enhancing Interoperability in Radiology through Segmentation Techniques [PDF]

open access: yes, 2007
An efficient information sharing environment can enhance interoperability within any organization. Healthcare organizations and hospitals, in particular, are no exception.
Kostagiolas, Petros A.   +2 more
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