Results 81 to 90 of about 169,019 (308)

Geodesic Information Flows: Spatially-Variant Graphs and Their Application to Segmentation and Fusion [PDF]

open access: yes, 2015
Clinical annotations, such as voxel-wise binary or probabilistic tissue segmentations, structural parcellations, pathological regionsof- interest and anatomical landmarks are key to many clinical studies.
Melbourne, A   +13 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Research on Medical Image Segmentation Based on SAM and Its Future Prospects

open access: yesBioengineering
The rapid advancement of prompt-based models in natural language processing and image generation has revolutionized the field of image segmentation.
Kangxu Fan   +5 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A novel framework for segmentation of small targets in medical images

open access: yesScientific Reports
Medical image segmentation represents a pivotal and intricate procedure in the domain of medical image processing and analysis. With the progression of artificial intelligence in recent years, the utilization of deep learning techniques for medical image
Longxuan Zhao   +10 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Medical image segmentation methods overview

open access: yesSistemnì Doslìdženâ ta Informacìjnì Tehnologìï, 2018
This article provides an overview of the modern medical image segmentation methods. The most popular methods such as multi-atlas based methods and deep learning approach are considered in more details.
Bohdan V. Chapaliuk, Yuriy P. Zaychenko
doaj   +1 more source

A novel neural network approach to cDNA microarray image segmentation [PDF]

open access: yes, 2013
This is the post-print version of the Article. The official published version can be accessed from the link below. Copyright @ 2013 Elsevier.Microarray technology has become a great source of information for biologists to understand the workings of DNA ...
Zineddin, B   +7 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Medical Image Segmentation Using Combined Level Set and Saliency Analysis

open access: yesIEEE Access
In the realm of computer vision, image segmentation has become a crucial task with widespread applications, particularly in medical imaging. Although there have been significant advancements in image segmentation methods, challenges persist in accurately
Aditi Joshi   +2 more
doaj   +1 more source

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