Results 111 to 120 of about 2,936,368 (282)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

A Review of Medical Image Registration for Different Modalities

Bioengineering
Medical image registration has become pivotal in recent years with the integration of various imaging modalities like X-ray, ultrasound, MRI, and CT scans, enabling comprehensive analysis and diagnosis of biological structures.
Fatemehzahra Darzi, Thomas Bocklitz
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

TNT++: A Spectral Super-Resolution Method Based on the Entropy of Pathological Images

IEEE Access
Spectral super-resolution is critical in transforming multispectral images into hyperspectral variants. Its profound importance is evident, yet its adoption in medical imaging reveals a palpable gap.
Huiyuan Zhang, Zhaohua Yang, Zeyuan Dong, Yijing Chen   +3 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Computer assisted pre-operative interactive 3-d planning of surgical procedures in neurosurgery

Zdravniški Vestnik, 2006
Background: Present paper describes our experiences with the use of three-dimensional (3D) reconstruction of medical images for pre-operative planning and intra-operative navigation in neurosurgery of cortical and sub-cortical tumors.Methods: In 10 ...
Tilen Žele, Boštjan Matos, Borut Prestor, Jernej Knific, Fajko F. Bajrović   +4 more
doaj  

Using Compressed JPEG and JPEG2000 Medical Images in Deep Learning: A Review

Applied Sciences
Machine Learning (ML), particularly Deep Learning (DL), has become increasingly integral to medical imaging, significantly enhancing diagnostic processes and treatment planning.
Ilona Anna Urbaniak
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Adaptive Gaussian Wiener Filter for CT-Scan Images with Gaussian Noise Variance

Journal of Informatics and Web Engineering
Medical imaging plays an important role in modern healthcare, with Computed Tomography (CT) being essential for high-resolution cross-sectional imaging.
Kai Liang Lew, Chung Yang Kew, Kok Swee Sim, Shing Chiang Tan   +3 more
doaj   +1 more source