Results 91 to 100 of about 8,748,059 (256)
, 2012 The authors are grateful to Dr. Deborah Rubens for her assistance and expertise in Radiology.The field of radiology dates back to 1896 with the first direct x-ray exposure of film by Roentgen.
Parker, Kevin J., Zhang, Man
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Finsler geometry on higher order tensor fields and applications to high angular resolution diffusion imaging. [PDF]
, 2009 We study 3D-multidirectional images, using Finsler geometry. The application considered here is in medical image analysis, specifically in High Angular Resolution Diffusion Imaging (HARDI) (Tuch et al. in Magn. Reson. Med.
Florack, L.M.J. +9 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Assessment of the effectiveness of medical simulators in the practical training of medical students: Preliminary results in MU-Varna [PDF]
, 2019 INTRODUCTION: Nowadays, simulators have become part of most medical universities’ educational strategy. In recent years, Medical University of Varna has been equipped with the most modern medical simulators, aiming to meet the practical training needs of
Chernogorova, Yanita; Medical University of Varna +2 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
‘Do you see what I see?’ Medical imaging: the interpretation of visual information [PDF]
Röntgen's discovery of x-rays in 1895, gave to medicine the extraordinary benefit of being able to see inside the living body without surgery. Over time, technology has added to the sophistication of imaging processes in medicine and we now have a wide ...
Manning, David J.
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Quantification of Biophysical Parameters in Medical Imaging
The second edition of this book offers six new chapters covering the latest developments in quantitative medical imaging, including artificial intelligence, MRI mapping, sonography, elastography and cardiac CT.
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