Results 51 to 60 of about 4,951,805 (294)

Evaluating visual analytics for health informatics applications: a systematic review from the American Medical Informatics Association Visual Analytics Working Group Task Force on Evaluation

J. Am. Medical Informatics Assoc., 2019
OBJECTIVE This article reports results from a systematic literature review related to the evaluation of data visualizations and visual analytics technologies within the health informatics domain.
Danny T. Y. Wu, Annie T. Chen, J. Manning, Gal Levy-Fix, Uba Backonja, D. Borland, Jesus J. Caban, D. Dowding, H. Hochheiser, Vadim Kagan, Swaminathan Kandaswamy, Manish Kumar, Alexis Nunez, E. Pan, D. Gotz   +14 more
semanticscholar   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Verpasste Chancen. Nachdenken über Fehlentwicklungen der Medizinischen Informatik

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2023
Fifty years ago medical informatics in Germany was second to none, was world-leading along with Sweden and the USA. Today we are “also-rans” regarding the digitalisation in medicine, have a low ranking. What is the cause?
Giere, Wolfgang
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Medizin dient der Gesundheit, Informatik der Daseinsgestaltung – Synergie in Dualität: Über das erste halbe Jahrhundert Medizinische Informatik Heidelberg/Heilbronn

GMS Medizinische Informatik, Biometrie und Epidemiologie
The Heidelberg-Heilbronn medical informatics program, whose foundation and development during its first 50 years are reported here, was initially established in 1972 as a diploma program, then converted into a consecutive bachelor’s and master’s program ...
Haux, Reinhold
doaj   +1 more source

European Federation of Medical Informatics Participation in European Projects – HosmartAI Project as an Experience

Applied Medical Informatics, 2023
The European Federation for Medical Informatics Association (EFMI) is the leading organisation in medical informatics in Europe and represents 29 countries, RSMI being an active and valuable member. EFMI is organized as a nonprofit organisation concerned
Lăcrămioara STOICU-TIVADAR, John MANTAS, Mihaela CRIŞAN-VIDA, Patrick WEBER, Thomas DESERNO, Jaime DELGADO, Carlos PARRA-CALDERON, Alfred WINTER, Arriel BENIS   +8 more
doaj  

Moving toward a United States strategic plan in primary care informatics: a White Paper of the Primary Care Informatics Working Group, American Medical Informatics Association

Journal of Innovation in Health Informatics, 2003
The Primary Care Informatics Working Group (PCIWG) of the American Medical Informatics Association (AMIA) has identified the absence of a national strategy for primary care informatics.
David Little, John Zapp, Henry Mullins, Alan Zuckerman, Sheila Teasdale, Kevin Johnson   +5 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

German Medical Informatics Initiative: Unlocking Data for Research and Health Care

Methods of Information in Medicine, 2018
Summary This article is part of the Focus Theme of Methods of Information in Medicine on the German Medical Informatics Initiative. The Medical Informatics Initiative of the German Federal Ministry of Education and Research will make use of the potential
Stefanie Gehring, R. Eulenfeld
semanticscholar   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source