Results 61 to 70 of about 4,299,186 (232)

A Complementarity‐Based Approach to De Novo Binder Design

Advanced Science, EarlyView.
A novel method for surface complementarity detection (HECTOR) enables highly efficient docking and design of protein interfaces. Applied to therapeutically relevant targets, this method yields de novo binders with potent antagonistic activity. As a first‐principles approach, HECTOR offers a training‐free solution to the binder design problem and is ...
Kateryna Maksymenko, Valeriia Hatskovska, Murray Coles, Narges Aghaallaei, Natalia Pashkovskaia, Natalia Borbarán‐Bravo, Matteo Pilz, Philip Bucher, Mareike Volz, Joana Pereira, Marcus D. Hartmann, Ghazaleh Tabatabai, Judith Feucht, Stefan Liebau, Patrick Müller, Andrei N. Lupas, Julia Skokowa, Mohammad ElGamacy   +17 more
wiley   +1 more source

Web Services and IT Management in Healthcare and Grid Computing [PDF]

Alma Ata Declaration on Primary Health Care defines , health as not just absence of disease but fitness at all levels i.e.Physically, mentally, Psychologically, spirtually, socially, and so on.
K., Srinivasan
core   +1 more source

BMC Medical Informatics and Decision Making

BMC Medical Informatics and Decision Making, 2014
Contributing reviewersThe editors of BMC Medical Informatics and Decision Making would like to thank all our reviewers who have contributed their time to the journal in Volume 13 (2013).
Irene Pala
semanticscholar   +1 more source

Fast pH‐Driven Solubilization Method of Realgar (As4S4) to Reduce the Toxicity of Arsenic [As(III)] for Medicinal Purposes

Advanced Science, EarlyView.
Arsenic trioxide transformed acute promyelocytic leukemia therapy and shows promise against HIV. A new method to solubilize the mineral realgar produces different arsenic species depleting the main arsenic target, nuclear PML protein, and retaining effects on leukemic and HIV reservoir cells, while minimizing off‐target damage.
Bojana Lucic, Douglas Santana Franciscato, Helton Pereira Nogueira, Lara Gallucci, Alceu Totti Silveira Junior, Asmaa Mohamed Ismail, Millie Robinson, Teresa Dallinger, Claudia Gutfleisch, Jochen Kurz, Maytê Toledo, Jessica Dias da Silva Ferraz, Mohammad Tarek, Danilo Dias, Ricardo Sobhie Diaz, Mahmoud ElHefnawi, Mattia Forcato, Hugo P Monteiro, Marina Lusic, Iart Luca Shytaj, Andrea Savarino   +20 more
wiley   +1 more source

Argumentation approaches for explanaible AI in medical informatics

Intelligent Systems with Applications, 2022
Luciano Caroprese, Eugenio Vocaturo, E. Zumpano   +2 more
semanticscholar   +1 more source

Contributions to the History of Medical Informatics

Medical Archives, 2014
Health professionals are able to make right decision in right time only if they posses prompt, accurate and up to date information about health status of patients and general population.
Silvije Vuletic
semanticscholar   +1 more source

A Two‐Component Pseudo‐Icosahedral Protein Nanocompartment with Variable Shell Composition and Irregular Tiling

Advanced Science, EarlyView.
The structure and assembly principles of a two‐component encapsulin nanocompartment shell are reported. The two‐component protein compartment self‐assembles from two distinct HK97‐fold shell proteins into a pseudo‐icosahedral protein shell with variable composition and irregular tiling.
Cassandra A. Dutcher, Michael P. Andreas, Tobias W. Giessen   +2 more
wiley   +1 more source

A Wearable AI‐Driven Mask with Humidity‐Sensing Respiratory Microphone for Non‐Vocal Communication

Advanced Science, EarlyView.
A wearable, plug‐and‐play respiratory microphone—featuring a gold nanoparticle‐based humidity sensor—facilitates voice‐free verbal communication for patients with impaired vocal fold function. Abstract Hoarseness and dysphonia caused by vocal cord conditions or laryngeal surgeries significantly hinder communication and quality of life.
Jianfei Wang, Hongyu Zhang, Xiaomin Wu, Mingyan Gao, He Wen, Zhibo Zhang, Kremena Makasheva, Wen Jung Li, Zuobin Wang   +8 more
wiley   +1 more source

A High‐Performance Garnet‐Based All‐Solid‐State Battery Fabricated Through Room‐Temperature Ultrasonic Welding

Advanced Science, EarlyView.
A room‐temperature ultrasonic treatment enhances the LiMg/LLZO interface, where the Mg framework and in situ formed Li2O/MgO interphase enable a record 4.45 mA cm−2 CCD and a stable cycling for over 1000 h at 1 mA cm−2. Combined with a fluorinated cathode interface, the ASSB delivers 153 mAh g−1 at 0.5 C with 90% capacity retention after 200 cycles ...
Tianlu Pang, Shufen Wu, Han Wu, Xiaobao Li, Yande Li, LiTao Yu, Hui Zhang, Yong Han, Zhi Guo, Nian Zhang   +9 more
wiley   +1 more source

The Scope and Direction of Health Informatics [PDF]

Health Informatics (HI) is a dynamic discipline based upon the medical sciences, information sciences, and cognitive sciences. Its domain is can broadly be defined as medical information management.
McGinnis, Patrick J.
core   +1 more source